Investigation of optimal gestational weight gain for twin pregnancy in Southwest China: a retrospective study
Abstract There is a lack of data on gestational weight gain (GWG) in twin pregnancies. We divided all the participants into two subgroups: the optimal outcome subgroup and the adverse outcome subgroup. They were also stratified according to prepregnancy body mass index (BMI): underweight (< 18.5 ...
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Nature Portfolio
2023-03-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-31766-7 |
| _version_ | 1797853956454481920 |
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| author | Li Gao Cuirong Lei Shuwei Zhou Qianqian Liao Lingwei Mei Qimei Zhong Xia Lan Ya Chen Lan Wang |
| author_facet | Li Gao Cuirong Lei Shuwei Zhou Qianqian Liao Lingwei Mei Qimei Zhong Xia Lan Ya Chen Lan Wang |
| author_sort | Li Gao |
| collection | DOAJ |
| description | Abstract There is a lack of data on gestational weight gain (GWG) in twin pregnancies. We divided all the participants into two subgroups: the optimal outcome subgroup and the adverse outcome subgroup. They were also stratified according to prepregnancy body mass index (BMI): underweight (< 18.5 kg/m2), normal weight (18.5–23.9 kg/m2), overweight (24–27.9 kg/m2), and obese (≥ 28 kg/m2). We used 2 steps to confirm the optimal range of GWG. The first step was proposing the optimal range of GWG using a statistical-based method (the interquartile range of GWG in the optimal outcome subgroup). The second step was confirming the proposed optimal range of GWG via compared the incidence of pregnancy complications in groups below or above the optimal GWG and analyzed the relationship between weekly GWG and pregnancy complications to validated the rationality of optimal weekly GWG through logistic regression. The optimal GWG calculated in our study was lower than that recommended by the Institute of Medicine. Except for the obese group, in the other 3 BMI groups, the overall disease incidence within the recommendation was lower than that outside the recommendation. Insufficient weekly GWG increased the risk of gestational diabetes mellitus, premature rupture of membranes, preterm birth and fetal growth restriction. Excessive weekly GWG increased the risk of gestational hypertension and preeclampsia. The association varied with prepregnancy BMI. In conclusion, we provide preliminary Chinese GWG optimal range which derived from twin-pregnant women with optimal outcomes(16–21.5 kg for underweight, 15–21.1 kg for normal weight, 13–20 kg for overweight), except for obesity, due to the limited sample size. |
| first_indexed | 2024-04-09T19:58:06Z |
| format | Article |
| id | doaj.art-f103e444262e4a98905c423584283d5e |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-09T19:58:06Z |
| publishDate | 2023-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-f103e444262e4a98905c423584283d5e2023-04-03T05:22:20ZengNature PortfolioScientific Reports2045-23222023-03-011311910.1038/s41598-023-31766-7Investigation of optimal gestational weight gain for twin pregnancy in Southwest China: a retrospective studyLi Gao0Cuirong Lei1Shuwei Zhou2Qianqian Liao3Lingwei Mei4Qimei Zhong5Xia Lan6Ya Chen7Lan Wang8Department of Obstetrics and Gynecology, Chongqing Health Center for Women and Children (Women and Children’s Hospital of Chongqing Medical University)Gynecological Oncology Center, Chongqing University Cancer HospitalDepartment of Obstetrics and Gynecology, Chongqing Health Center for Women and Children (Women and Children’s Hospital of Chongqing Medical University)Department of Obstetrics and Gynecology, Chongqing Health Center for Women and Children (Women and Children’s Hospital of Chongqing Medical University)Department of Obstetrics and Gynecology, Chongqing Health Center for Women and Children (Women and Children’s Hospital of Chongqing Medical University)Department of Obstetrics and Gynecology, Chongqing Health Center for Women and Children (Women and Children’s Hospital of Chongqing Medical University)Department of Obstetrics and Gynecology, Chongqing Health Center for Women and Children (Women and Children’s Hospital of Chongqing Medical University)Department of Obstetrics and Gynecology, Chongqing Health Center for Women and Children (Women and Children’s Hospital of Chongqing Medical University)Department of Obstetrics and Gynecology, Chongqing Health Center for Women and Children (Women and Children’s Hospital of Chongqing Medical University)Abstract There is a lack of data on gestational weight gain (GWG) in twin pregnancies. We divided all the participants into two subgroups: the optimal outcome subgroup and the adverse outcome subgroup. They were also stratified according to prepregnancy body mass index (BMI): underweight (< 18.5 kg/m2), normal weight (18.5–23.9 kg/m2), overweight (24–27.9 kg/m2), and obese (≥ 28 kg/m2). We used 2 steps to confirm the optimal range of GWG. The first step was proposing the optimal range of GWG using a statistical-based method (the interquartile range of GWG in the optimal outcome subgroup). The second step was confirming the proposed optimal range of GWG via compared the incidence of pregnancy complications in groups below or above the optimal GWG and analyzed the relationship between weekly GWG and pregnancy complications to validated the rationality of optimal weekly GWG through logistic regression. The optimal GWG calculated in our study was lower than that recommended by the Institute of Medicine. Except for the obese group, in the other 3 BMI groups, the overall disease incidence within the recommendation was lower than that outside the recommendation. Insufficient weekly GWG increased the risk of gestational diabetes mellitus, premature rupture of membranes, preterm birth and fetal growth restriction. Excessive weekly GWG increased the risk of gestational hypertension and preeclampsia. The association varied with prepregnancy BMI. In conclusion, we provide preliminary Chinese GWG optimal range which derived from twin-pregnant women with optimal outcomes(16–21.5 kg for underweight, 15–21.1 kg for normal weight, 13–20 kg for overweight), except for obesity, due to the limited sample size.https://doi.org/10.1038/s41598-023-31766-7 |
| spellingShingle | Li Gao Cuirong Lei Shuwei Zhou Qianqian Liao Lingwei Mei Qimei Zhong Xia Lan Ya Chen Lan Wang Investigation of optimal gestational weight gain for twin pregnancy in Southwest China: a retrospective study Scientific Reports |
| title | Investigation of optimal gestational weight gain for twin pregnancy in Southwest China: a retrospective study |
| title_full | Investigation of optimal gestational weight gain for twin pregnancy in Southwest China: a retrospective study |
| title_fullStr | Investigation of optimal gestational weight gain for twin pregnancy in Southwest China: a retrospective study |
| title_full_unstemmed | Investigation of optimal gestational weight gain for twin pregnancy in Southwest China: a retrospective study |
| title_short | Investigation of optimal gestational weight gain for twin pregnancy in Southwest China: a retrospective study |
| title_sort | investigation of optimal gestational weight gain for twin pregnancy in southwest china a retrospective study |
| url | https://doi.org/10.1038/s41598-023-31766-7 |
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