Pathophysiological Aspects of Hyperoxia in Anesthesiologist-Reanimatologist's Practice
The aim of the review is to present potentially negative effects of hyperoxia in various groups of critically ill patients, including those after cardiac arrest, brain injury or stroke, and in cases of sepsis. It was noted that in cases of these pathological processes and nosological forms there wer...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2017-06-01
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| Series: | Общая реаниматология |
| Subjects: | |
| Online Access: | https://www.reanimatology.com/rmt/article/view/1594 |
| Summary: | The aim of the review is to present potentially negative effects of hyperoxia in various groups of critically ill patients, including those after cardiac arrest, brain injury or stroke, and in cases of sepsis. It was noted that in cases of these pathological processes and nosological forms there were evidences that hyperoxia could have a damaging effect, and that oxygen should be prescribed on an individual basis depending on the assessment of the current oxy- gen requirement. It has been established that hyperoxia commonly represent the last reserve to abrogate the progressive hypoxia. The mechanisms of adaptation of the body to hyperoxia are described and the possibility to reduce the toxic effects of oxygen with the aid of succinates is discussed. |
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| ISSN: | 1813-9779 2411-7110 |