Pathophysiological Aspects of Hyperoxia in Anesthesiologist-Reanimatologist's Practice

The aim of the review is to present potentially negative effects of hyperoxia in various groups of critically ill patients, including those after cardiac arrest, brain injury or stroke, and in cases of sepsis. It was noted that in cases of these pathological processes and nosological forms there wer...

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Main Authors: Vladimir T. Dolgikh, Natalia V. Govorova, Yury P. Orlov, Olga V. Korpacheva, Galina N. Dorovskikh, Anton V. Ershov
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2017-06-01
Series:Общая реаниматология
Subjects:
Online Access:https://www.reanimatology.com/rmt/article/view/1594
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author Vladimir T. Dolgikh
Natalia V. Govorova
Yury P. Orlov
Olga V. Korpacheva
Galina N. Dorovskikh
Anton V. Ershov
author_facet Vladimir T. Dolgikh
Natalia V. Govorova
Yury P. Orlov
Olga V. Korpacheva
Galina N. Dorovskikh
Anton V. Ershov
author_sort Vladimir T. Dolgikh
collection DOAJ
description The aim of the review is to present potentially negative effects of hyperoxia in various groups of critically ill patients, including those after cardiac arrest, brain injury or stroke, and in cases of sepsis. It was noted that in cases of these pathological processes and nosological forms there were evidences that hyperoxia could have a damaging effect, and that oxygen should be prescribed on an individual basis depending on the assessment of the current oxy- gen requirement. It has been established that hyperoxia commonly represent the last reserve to abrogate the progressive hypoxia. The mechanisms of adaptation of the body to hyperoxia are described and the possibility to reduce the toxic effects of oxygen with the aid of succinates is discussed.
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spelling doaj.art-f1064507608c439183d61e9df1a90c282023-03-13T09:32:54ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102017-06-01133839310.15360/1813-9779-2017-3-83-931560Pathophysiological Aspects of Hyperoxia in Anesthesiologist-Reanimatologist's PracticeVladimir T. Dolgikh0Natalia V. Govorova1Yury P. Orlov2Olga V. Korpacheva3Galina N. Dorovskikh4Anton V. Ershov5Омский государственный медицинский университет Минздрава РоссииОмский государственный медицинский университет Минздрава РоссииОмский государственный медицинский университет Минздрава РоссииОмский государственный медицинский университет Минздрава РоссииОмский государственный медицинский университет Минздрава РоссииОмский государственный медицинский университет Минздрава РоссииThe aim of the review is to present potentially negative effects of hyperoxia in various groups of critically ill patients, including those after cardiac arrest, brain injury or stroke, and in cases of sepsis. It was noted that in cases of these pathological processes and nosological forms there were evidences that hyperoxia could have a damaging effect, and that oxygen should be prescribed on an individual basis depending on the assessment of the current oxy- gen requirement. It has been established that hyperoxia commonly represent the last reserve to abrogate the progressive hypoxia. The mechanisms of adaptation of the body to hyperoxia are described and the possibility to reduce the toxic effects of oxygen with the aid of succinates is discussed.https://www.reanimatology.com/rmt/article/view/1594гипоксиягипероксиясукцинаты
spellingShingle Vladimir T. Dolgikh
Natalia V. Govorova
Yury P. Orlov
Olga V. Korpacheva
Galina N. Dorovskikh
Anton V. Ershov
Pathophysiological Aspects of Hyperoxia in Anesthesiologist-Reanimatologist's Practice
Общая реаниматология
гипоксия
гипероксия
сукцинаты
title Pathophysiological Aspects of Hyperoxia in Anesthesiologist-Reanimatologist's Practice
title_full Pathophysiological Aspects of Hyperoxia in Anesthesiologist-Reanimatologist's Practice
title_fullStr Pathophysiological Aspects of Hyperoxia in Anesthesiologist-Reanimatologist's Practice
title_full_unstemmed Pathophysiological Aspects of Hyperoxia in Anesthesiologist-Reanimatologist's Practice
title_short Pathophysiological Aspects of Hyperoxia in Anesthesiologist-Reanimatologist's Practice
title_sort pathophysiological aspects of hyperoxia in anesthesiologist reanimatologist s practice
topic гипоксия
гипероксия
сукцинаты
url https://www.reanimatology.com/rmt/article/view/1594
work_keys_str_mv AT vladimirtdolgikh pathophysiologicalaspectsofhyperoxiainanesthesiologistreanimatologistspractice
AT nataliavgovorova pathophysiologicalaspectsofhyperoxiainanesthesiologistreanimatologistspractice
AT yuryporlov pathophysiologicalaspectsofhyperoxiainanesthesiologistreanimatologistspractice
AT olgavkorpacheva pathophysiologicalaspectsofhyperoxiainanesthesiologistreanimatologistspractice
AT galinandorovskikh pathophysiologicalaspectsofhyperoxiainanesthesiologistreanimatologistspractice
AT antonvershov pathophysiologicalaspectsofhyperoxiainanesthesiologistreanimatologistspractice