Prehabilitation to Improve Outcomes of Patients with Gynaecological Cancer: A New Window of Opportunity?
The literature evaluating the effect of prehabilitation programmes on postoperative outcomes and quality of life of patients with gynaecological cancer undergoing surgery was reviewed. Databases including Pubmed, Medline, EMBASE (Ovid) and PsycINFO were systematically searched to identify studies ev...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/14/14/3448 |
| _version_ | 1797440440130076672 |
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| author | Joëlle Dhanis Nathaniel Keidan Dominic Blake Stuart Rundle Dieuwke Strijker Maaike van Ham Johanna M. A. Pijnenborg Anke Smits |
| author_facet | Joëlle Dhanis Nathaniel Keidan Dominic Blake Stuart Rundle Dieuwke Strijker Maaike van Ham Johanna M. A. Pijnenborg Anke Smits |
| author_sort | Joëlle Dhanis |
| collection | DOAJ |
| description | The literature evaluating the effect of prehabilitation programmes on postoperative outcomes and quality of life of patients with gynaecological cancer undergoing surgery was reviewed. Databases including Pubmed, Medline, EMBASE (Ovid) and PsycINFO were systematically searched to identify studies evaluating the effect of prehabilitation programmes on patients with gynaecological cancer. Both unimodal and multimodal prehabilitation programmes were included encompassing physical exercise and nutritional and psychological support. Primary outcomes were surgical complications and quality of life. Secondary outcomes were anthropometric changes and adherence to the prehabilitation programme. Seven studies fulfilled the inclusion criteria, comprising 580 patients. Included studies were nonrandomised prospective studies (n = 4), retrospective studies (n = 2) and one case report. Unimodal programmes and multimodal programmes were included. In patients with ovarian cancer, multimodal prehabilitation resulted in significantly reduced hospital stay and time to chemotherapy. In patients with endometrial and cervical cancer, prehabilitation was associated with significant weight loss, but had no significant effects on surgical complications or mortality. No adverse events of the programmes were reported. Evidence on the effect of prehabilitation for patients with gynaecological cancer is limited. Future studies are needed to determine the effects on postoperative complications and quality of life. |
| first_indexed | 2024-03-09T12:07:11Z |
| format | Article |
| id | doaj.art-f10857079408413a8c02e972a52e9797 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-09T12:07:11Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-f10857079408413a8c02e972a52e97972023-11-30T22:56:40ZengMDPI AGCancers2072-66942022-07-011414344810.3390/cancers14143448Prehabilitation to Improve Outcomes of Patients with Gynaecological Cancer: A New Window of Opportunity?Joëlle Dhanis0Nathaniel Keidan1Dominic Blake2Stuart Rundle3Dieuwke Strijker4Maaike van Ham5Johanna M. A. Pijnenborg6Anke Smits7Department of Obstetrics and Gynaecology, Radboud University Medical Centre, 6525 GA Nijmegen, The NetherlandsDepartment of Gynaecological Oncology, Queen Elizabeth Hospital, Gateshead NE9 6SX, UKDepartment of Gynaecological Oncology, Queen Elizabeth Hospital, Gateshead NE9 6SX, UKDepartment of Gynaecological Oncology, Queen Elizabeth Hospital, Gateshead NE9 6SX, UKDepartment of Surgery, Radboud University Medical Centre, 6525 GA Nijmegen, The NetherlandsDepartment of Obstetrics and Gynaecology, Radboud University Medical Centre, 6525 GA Nijmegen, The NetherlandsDepartment of Obstetrics and Gynaecology, Radboud University Medical Centre, 6525 GA Nijmegen, The NetherlandsDepartment of Obstetrics and Gynaecology, Radboud University Medical Centre, 6525 GA Nijmegen, The NetherlandsThe literature evaluating the effect of prehabilitation programmes on postoperative outcomes and quality of life of patients with gynaecological cancer undergoing surgery was reviewed. Databases including Pubmed, Medline, EMBASE (Ovid) and PsycINFO were systematically searched to identify studies evaluating the effect of prehabilitation programmes on patients with gynaecological cancer. Both unimodal and multimodal prehabilitation programmes were included encompassing physical exercise and nutritional and psychological support. Primary outcomes were surgical complications and quality of life. Secondary outcomes were anthropometric changes and adherence to the prehabilitation programme. Seven studies fulfilled the inclusion criteria, comprising 580 patients. Included studies were nonrandomised prospective studies (n = 4), retrospective studies (n = 2) and one case report. Unimodal programmes and multimodal programmes were included. In patients with ovarian cancer, multimodal prehabilitation resulted in significantly reduced hospital stay and time to chemotherapy. In patients with endometrial and cervical cancer, prehabilitation was associated with significant weight loss, but had no significant effects on surgical complications or mortality. No adverse events of the programmes were reported. Evidence on the effect of prehabilitation for patients with gynaecological cancer is limited. Future studies are needed to determine the effects on postoperative complications and quality of life.https://www.mdpi.com/2072-6694/14/14/3448prehabilitationgynaecological cancerendometrial cancerovarian cancercervical cancerquality of life |
| spellingShingle | Joëlle Dhanis Nathaniel Keidan Dominic Blake Stuart Rundle Dieuwke Strijker Maaike van Ham Johanna M. A. Pijnenborg Anke Smits Prehabilitation to Improve Outcomes of Patients with Gynaecological Cancer: A New Window of Opportunity? Cancers prehabilitation gynaecological cancer endometrial cancer ovarian cancer cervical cancer quality of life |
| title | Prehabilitation to Improve Outcomes of Patients with Gynaecological Cancer: A New Window of Opportunity? |
| title_full | Prehabilitation to Improve Outcomes of Patients with Gynaecological Cancer: A New Window of Opportunity? |
| title_fullStr | Prehabilitation to Improve Outcomes of Patients with Gynaecological Cancer: A New Window of Opportunity? |
| title_full_unstemmed | Prehabilitation to Improve Outcomes of Patients with Gynaecological Cancer: A New Window of Opportunity? |
| title_short | Prehabilitation to Improve Outcomes of Patients with Gynaecological Cancer: A New Window of Opportunity? |
| title_sort | prehabilitation to improve outcomes of patients with gynaecological cancer a new window of opportunity |
| topic | prehabilitation gynaecological cancer endometrial cancer ovarian cancer cervical cancer quality of life |
| url | https://www.mdpi.com/2072-6694/14/14/3448 |
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