Identification of common stria vascularis cellular alteration in sensorineural hearing loss based on ScRNA-seq

Identification of common stria vascularis cellular alteration in sensorineural hearing loss based on ScRNA-seq

Abstract Background The stria vascularis (SV), located in the lateral wall of the cochlea, maintains cochlear fluid homeostasis and mechanoelectrical transduction (MET) activity required for sound wave conduction. The pathogenesis of a number of human inheritable deafness syndromes, age related hear...

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Bibliographic Details
Main Authors: Xi Gu, Kanglun Jiang, Ruru Chen, Zhifeng Chen, Xianmin Wu, Haijie Xiang, Xinsheng Huang, Benyu Nan
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Genomics
Subjects:
Sensorineural hearing loss (SNHL)
Stria vascularis
ScRNA-seq
Transcription factors (TF)
Cell‒cell communication
Online Access:https://doi.org/10.1186/s12864-024-10122-7

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