The regulatory capacity of B cells directs the aggressiveness of CLL

The regulatory capacity of B cells directs the aggressiveness of CLL

Chronic lymphocytic leukemia (CLL) is associated with abnormal T-cell responses responsible for defective anti-tumor activities. Intriguingly, CLL B cells share phenotypical characteristics with regulatory B (Breg) cells suggesting that they might negatively control the T-cell activation and immune...

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Bibliographic Details
Main Authors: Audrey Mohr, Marie Cumin, Cristina Bagacean, Pierre Pochard, Christelle Le Dantec, Sophie Hillion, Yves Renaudineau, Christian Berthou, Adrian Tempescul, Hussam Saad, Jacques-Olivier Pers, Anne Bordron, Christophe Jamin
Format: Article
Language:English
Published: Taylor & Francis Group 2019-03-01
Series:OncoImmunology
Subjects:
regulatory capacity
b cells
cll
aggressiveness
tlr9
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1554968

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