Effects of PCSK9 inhibitors on metabolic-associated fatty liver disease: a short review

Metabolic-associated fatty liver disease (MAFLD), previously known as non-alcoholic fatty liver disease, is a significant epidemiological problem and a well-known cardiovascular risk factor. The increasing number of cases creates the need for new therapeutic methods aimed at improving patient outcom...

Full description

Bibliographic Details
Main Authors: Ewelina Jakielska, Paweł Głuszak, Marta Walczak, Wiesław Bryl
Format: Article
Language:English
Published: Termedia Publishing House 2023-03-01
Series:Gastroenterology Review
Subjects:
Online Access:https://www.termedia.pl/Effects-of-PCSK9-inhibitors-on-metabolic-associated-fatty-liver-disease-a-short-review,41,50394,1,1.html
_version_ 1797692363298045952
author Ewelina Jakielska
Paweł Głuszak
Marta Walczak
Wiesław Bryl
author_facet Ewelina Jakielska
Paweł Głuszak
Marta Walczak
Wiesław Bryl
author_sort Ewelina Jakielska
collection DOAJ
description Metabolic-associated fatty liver disease (MAFLD), previously known as non-alcoholic fatty liver disease, is a significant epidemiological problem and a well-known cardiovascular risk factor. The increasing number of cases creates the need for new therapeutic methods aimed at improving patient outcomes. Recent studies have highlighted the relationship between MAFLD and proprotein convertase subtilisin/kexin type 9 (PCSK9). Based on the available data, PCSK9 inhibitors appear to have beneficial effects in patients with MAFLD, and they may be a treatment option in the future. Further research is necessary to better evaluate the efficiency of PCSK9 inhibitors in MAFLD treatment.
first_indexed 2024-03-12T02:27:32Z
format Article
id doaj.art-f10a8b3be4f34420be2e744f4557997d
institution Directory Open Access Journal
issn 1895-5770
1897-4317
language English
last_indexed 2024-03-12T02:27:32Z
publishDate 2023-03-01
publisher Termedia Publishing House
record_format Article
series Gastroenterology Review
spelling doaj.art-f10a8b3be4f34420be2e744f4557997d2023-09-05T11:50:44ZengTermedia Publishing HouseGastroenterology Review1895-57701897-43172023-03-0118214815310.5114/pg.2023.12605450394Effects of PCSK9 inhibitors on metabolic-associated fatty liver disease: a short reviewEwelina JakielskaPaweł GłuszakMarta WalczakWiesław BrylMetabolic-associated fatty liver disease (MAFLD), previously known as non-alcoholic fatty liver disease, is a significant epidemiological problem and a well-known cardiovascular risk factor. The increasing number of cases creates the need for new therapeutic methods aimed at improving patient outcomes. Recent studies have highlighted the relationship between MAFLD and proprotein convertase subtilisin/kexin type 9 (PCSK9). Based on the available data, PCSK9 inhibitors appear to have beneficial effects in patients with MAFLD, and they may be a treatment option in the future. Further research is necessary to better evaluate the efficiency of PCSK9 inhibitors in MAFLD treatment.https://www.termedia.pl/Effects-of-PCSK9-inhibitors-on-metabolic-associated-fatty-liver-disease-a-short-review,41,50394,1,1.htmlnon-alcoholic fatty liver disease fatty liver pcsk9.
spellingShingle Ewelina Jakielska
Paweł Głuszak
Marta Walczak
Wiesław Bryl
Effects of PCSK9 inhibitors on metabolic-associated fatty liver disease: a short review
Gastroenterology Review
non-alcoholic fatty liver disease
fatty liver
pcsk9.
title Effects of PCSK9 inhibitors on metabolic-associated fatty liver disease: a short review
title_full Effects of PCSK9 inhibitors on metabolic-associated fatty liver disease: a short review
title_fullStr Effects of PCSK9 inhibitors on metabolic-associated fatty liver disease: a short review
title_full_unstemmed Effects of PCSK9 inhibitors on metabolic-associated fatty liver disease: a short review
title_short Effects of PCSK9 inhibitors on metabolic-associated fatty liver disease: a short review
title_sort effects of pcsk9 inhibitors on metabolic associated fatty liver disease a short review
topic non-alcoholic fatty liver disease
fatty liver
pcsk9.
url https://www.termedia.pl/Effects-of-PCSK9-inhibitors-on-metabolic-associated-fatty-liver-disease-a-short-review,41,50394,1,1.html
work_keys_str_mv AT ewelinajakielska effectsofpcsk9inhibitorsonmetabolicassociatedfattyliverdiseaseashortreview
AT pawełgłuszak effectsofpcsk9inhibitorsonmetabolicassociatedfattyliverdiseaseashortreview
AT martawalczak effectsofpcsk9inhibitorsonmetabolicassociatedfattyliverdiseaseashortreview
AT wiesławbryl effectsofpcsk9inhibitorsonmetabolicassociatedfattyliverdiseaseashortreview