Feasibility of Coronary Artery Calcium Scoring on Dual-Energy Chest Computed Tomography: A Prospective Comparison with Electrocardiogram-Gated Calcium Score Computed Tomography

<b>Rationale and Objectives</b>: This study aimed to evaluate the feasibility of assessment using the coronary artery calcium score (CACS) in dual-energy chest computed tomography (CT). <b>Materials and Methods</b>: We prospectively enrolled 30 patients (19 male, 11 female; m...

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Main Authors: Sun Yong Lee, Tae Hoon Kim, Kyunghwa Han, Jae Min Shin, Ji Young Kim, Daein Kim, Chul Hwan Park
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/10/4/653
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author Sun Yong Lee
Tae Hoon Kim
Kyunghwa Han
Jae Min Shin
Ji Young Kim
Daein Kim
Chul Hwan Park
author_facet Sun Yong Lee
Tae Hoon Kim
Kyunghwa Han
Jae Min Shin
Ji Young Kim
Daein Kim
Chul Hwan Park
author_sort Sun Yong Lee
collection DOAJ
description <b>Rationale and Objectives</b>: This study aimed to evaluate the feasibility of assessment using the coronary artery calcium score (CACS) in dual-energy chest computed tomography (CT). <b>Materials and Methods</b>: We prospectively enrolled 30 patients (19 male, 11 female; mean age, 63.73 ± 9.40 years) who clinically required contrast-enhanced chest CT. The patients underwent electrocardiogram-gated cardiac calcium-scoring CT with a slice thickness of 2.5 mm followed by a sequentially non-gated contrast-enhanced dual-energy chest CT using 140/80 fast kVp switching technology with slice thicknesses of 1.25 mm and 2.5 mm. Virtual unenhanced (VUE) images were then reconstructed from the dual-energy CT using the material suppressed iodine (MSI) technique. <b>Results</b>: The mean heart rates were 63.33 ± 12.01 beats per minute. The mean CACS on the coronary calcium-scoring CT was 361.1 ± 435.5, and CACSs of the VUE images were 76.8 ± 128.6 (2.5 mm slice) and 108.7 ± 165.1 (1.25 mm slice). The correlation coefficients of CACS between the coronary calcium-scoring CT with the VUE 2.5 mm and 1.25 mm images were 0.888 and 0.904, respectively. The inter-observer agreements for the calcium score measurement between the calcium-scoring CT, VUE 2.5 mm, and VUE 1.25 mm were 1.000, 0.999, and 1.000, respectively. <b>Conclusions</b>: In conclusion, assessment of CACS using dual-energy chest CT might be feasible when using MSI virtual unenhanced dual-energy chest CT images with a slice thickness of 1.25 mm.
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spelling doaj.art-f10bd6226404482b96ad89c20e3417822023-12-03T12:55:54ZengMDPI AGJournal of Clinical Medicine2077-03832021-02-0110465310.3390/jcm10040653Feasibility of Coronary Artery Calcium Scoring on Dual-Energy Chest Computed Tomography: A Prospective Comparison with Electrocardiogram-Gated Calcium Score Computed TomographySun Yong Lee0Tae Hoon Kim1Kyunghwa Han2Jae Min Shin3Ji Young Kim4Daein Kim5Chul Hwan Park6Department of Radiology and The Research Institute of Radiological Science, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, KoreaDepartment of Radiology and The Research Institute of Radiological Science, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, KoreaDepartment of Radiology and The Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, KoreaDepartment of Radiology and The Research Institute of Radiological Science, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, KoreaDepartment of Radiology and The Research Institute of Radiological Science, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, KoreaDepartment of Radiology and The Research Institute of Radiological Science, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, KoreaDepartment of Radiology and The Research Institute of Radiological Science, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Korea<b>Rationale and Objectives</b>: This study aimed to evaluate the feasibility of assessment using the coronary artery calcium score (CACS) in dual-energy chest computed tomography (CT). <b>Materials and Methods</b>: We prospectively enrolled 30 patients (19 male, 11 female; mean age, 63.73 ± 9.40 years) who clinically required contrast-enhanced chest CT. The patients underwent electrocardiogram-gated cardiac calcium-scoring CT with a slice thickness of 2.5 mm followed by a sequentially non-gated contrast-enhanced dual-energy chest CT using 140/80 fast kVp switching technology with slice thicknesses of 1.25 mm and 2.5 mm. Virtual unenhanced (VUE) images were then reconstructed from the dual-energy CT using the material suppressed iodine (MSI) technique. <b>Results</b>: The mean heart rates were 63.33 ± 12.01 beats per minute. The mean CACS on the coronary calcium-scoring CT was 361.1 ± 435.5, and CACSs of the VUE images were 76.8 ± 128.6 (2.5 mm slice) and 108.7 ± 165.1 (1.25 mm slice). The correlation coefficients of CACS between the coronary calcium-scoring CT with the VUE 2.5 mm and 1.25 mm images were 0.888 and 0.904, respectively. The inter-observer agreements for the calcium score measurement between the calcium-scoring CT, VUE 2.5 mm, and VUE 1.25 mm were 1.000, 0.999, and 1.000, respectively. <b>Conclusions</b>: In conclusion, assessment of CACS using dual-energy chest CT might be feasible when using MSI virtual unenhanced dual-energy chest CT images with a slice thickness of 1.25 mm.https://www.mdpi.com/2077-0383/10/4/653coronary artery calcium scorecorrelation coefficientdual-energy computed tomographyECG-gated cardiac CTwide-detector CT
spellingShingle Sun Yong Lee
Tae Hoon Kim
Kyunghwa Han
Jae Min Shin
Ji Young Kim
Daein Kim
Chul Hwan Park
Feasibility of Coronary Artery Calcium Scoring on Dual-Energy Chest Computed Tomography: A Prospective Comparison with Electrocardiogram-Gated Calcium Score Computed Tomography
Journal of Clinical Medicine
coronary artery calcium score
correlation coefficient
dual-energy computed tomography
ECG-gated cardiac CT
wide-detector CT
title Feasibility of Coronary Artery Calcium Scoring on Dual-Energy Chest Computed Tomography: A Prospective Comparison with Electrocardiogram-Gated Calcium Score Computed Tomography
title_full Feasibility of Coronary Artery Calcium Scoring on Dual-Energy Chest Computed Tomography: A Prospective Comparison with Electrocardiogram-Gated Calcium Score Computed Tomography
title_fullStr Feasibility of Coronary Artery Calcium Scoring on Dual-Energy Chest Computed Tomography: A Prospective Comparison with Electrocardiogram-Gated Calcium Score Computed Tomography
title_full_unstemmed Feasibility of Coronary Artery Calcium Scoring on Dual-Energy Chest Computed Tomography: A Prospective Comparison with Electrocardiogram-Gated Calcium Score Computed Tomography
title_short Feasibility of Coronary Artery Calcium Scoring on Dual-Energy Chest Computed Tomography: A Prospective Comparison with Electrocardiogram-Gated Calcium Score Computed Tomography
title_sort feasibility of coronary artery calcium scoring on dual energy chest computed tomography a prospective comparison with electrocardiogram gated calcium score computed tomography
topic coronary artery calcium score
correlation coefficient
dual-energy computed tomography
ECG-gated cardiac CT
wide-detector CT
url https://www.mdpi.com/2077-0383/10/4/653
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