Synthesis and Biochemical Evaluation of Lid-Open D-Amino Acid Oxidase Inhibitors
Most of the known inhibitors of D-amino acid oxidase (DAAO) are small polar molecules recognized by the active site of the enzyme. More recently a new class of DAAO inhibitors has been disclosed that interacts with loop 218−224 at the top of the binding pocket. These compounds have a significantly l...
Main Authors: | Bence Szilágyi, Csilla Hargitai, Ádám A. Kelemen, Anita Rácz, György G. Ferenczy, Balázs Volk, György M. Keserű |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-01-01
|
Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/24/2/290 |
Similar Items
-
Malignant appearing benign lid tumor – An isolated upper lid schwannoma
by: Sahil Agrawal, et al.
Published: (2023-01-01) -
New Derivatives of 3,4-Dihydroisoquinoline-3-carboxylic Acid with Free-Radical Scavenging, D-Amino Acid Oxidase, Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activity
by: Jolanta Solecka, et al.
Published: (2014-09-01) -
Methods for the Detection of D-Amino-Acid Oxidase
by: Konno Ryuichi
Published: (1998-01-01) -
Lid wiper epitheliopathy in symptomatic and asymptomatic dry eye subjects
by: Vandana Kamath, et al.
Published: (2023-01-01) -
A Framework Based on LIDs and Storage Pumping Stations for Urban Waterlogging
by: Huayue Li, et al.
Published: (2024-03-01)