Skeletal muscle‐specific DJ‐1 ablation‐induced atrogenes expression and mitochondrial dysfunction contributing to muscular atrophy

Skeletal muscle‐specific DJ‐1 ablation‐induced atrogenes expression and mitochondrial dysfunction contributing to muscular atrophy

Abstract Background DJ‐1 is a causative gene for Parkinson's disease. DJ‐1‐deficient mice develop gait‐associated progressive behavioural abnormalities and hypoactive forearm grip strength. However, underlying activity mechanisms are not fully explored. Methods Western blotting and quantitative...

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Bibliographic Details
Main Authors: Shuang Zhang, Hongmei Yan, Jiyang Ding, Ruwen Wang, Yonghao Feng, Xinyi Zhang, Xingyu Kong, Hongyu Gong, Xiaodan Lu, Alice Ma, Yinghui Hua, Huan Liu, Jiani Guo, Huanqing Gao, Zhenqi Zhou, Ru Wang, Peijie Chen, Tiemin Liu, Xingxing Kong
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Atrogenes
Atrophy
DJ‐1
Skeletal muscle
Online Access:https://doi.org/10.1002/jcsm.13290

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