Sustainable Green Synthesis of Yttrium Oxide (Y<sub>2</sub>O<sub>3</sub>) Nanoparticles Using <i>Lantana camara</i> Leaf Extracts: Physicochemical Characterization, Photocatalytic Degradation, Antibacterial, and Anticancer Potency
Due to their appropriate physicochemical properties, nanoparticles are used in nanomedicine to develop drug delivery systems for anticancer therapy. In biomedical applications, metal oxide nanoparticles are used as powerful and flexible multipurpose agents. This work described a green synthesis of Y...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/12/14/2393 |
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| author | Rajakumar Govindasamy Mydhili Govindarasu Salman S. Alharthi Preeyanghaa Mani Neppolian Bernaurdshaw Thandapani Gomathi Mohammad Azam Ansari Mohammad N. Alomary Banan Atwah M. Shaheer Malik V. Devi Rajeswari Kaliaperumal Rekha Saleh A. Ahmed Muthu Thiruvengadam |
| author_facet | Rajakumar Govindasamy Mydhili Govindarasu Salman S. Alharthi Preeyanghaa Mani Neppolian Bernaurdshaw Thandapani Gomathi Mohammad Azam Ansari Mohammad N. Alomary Banan Atwah M. Shaheer Malik V. Devi Rajeswari Kaliaperumal Rekha Saleh A. Ahmed Muthu Thiruvengadam |
| author_sort | Rajakumar Govindasamy |
| collection | DOAJ |
| description | Due to their appropriate physicochemical properties, nanoparticles are used in nanomedicine to develop drug delivery systems for anticancer therapy. In biomedical applications, metal oxide nanoparticles are used as powerful and flexible multipurpose agents. This work described a green synthesis of Y<sub>2</sub>O<sub>3</sub> nanoparticles (NPs) using the sol-gel technique with the use of aqueous leaf extracts of <i>Lantana camara</i> L (LC). These nanoparticles were characterized with the aid of different methods, including UV, X-ray diffraction (XRD), Fourier transformed infrared spectroscopy (FTIR), transmitted electron microscopy (TEM), and photocatalytic degradation. Y<sub>2</sub>O<sub>3</sub> nanoparticles showed excellent antibacterial activity against Gram-positive <i>Bacillus subtilis</i> and Gram-negative <i>Escherichia coli</i> with a 10 to 15 mm inhibitory zone. Green Y<sub>2</sub>O<sub>3</sub> NPs were released with a 4 h lag time and 80% sustained release rate, indicating that they could be used in drug delivery. In addition, the bioavailability of green Y<sub>2</sub>O<sub>3</sub> NPs was investigated using cell viability in cervical cancer cell lines. These green-synthesized Y<sub>2</sub>O<sub>3</sub> NPs demonstrated photocatalytic degradation, antibacterial, and anticancer properties. |
| first_indexed | 2024-03-09T10:14:55Z |
| format | Article |
| id | doaj.art-f114772efd8d4647a9df37968da6b2c1 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-09T10:14:55Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-f114772efd8d4647a9df37968da6b2c12023-12-01T22:31:06ZengMDPI AGNanomaterials2079-49912022-07-011214239310.3390/nano12142393Sustainable Green Synthesis of Yttrium Oxide (Y<sub>2</sub>O<sub>3</sub>) Nanoparticles Using <i>Lantana camara</i> Leaf Extracts: Physicochemical Characterization, Photocatalytic Degradation, Antibacterial, and Anticancer PotencyRajakumar Govindasamy0Mydhili Govindarasu1Salman S. Alharthi2Preeyanghaa Mani3Neppolian Bernaurdshaw4Thandapani Gomathi5Mohammad Azam Ansari6Mohammad N. Alomary7Banan Atwah8M. Shaheer Malik9V. Devi Rajeswari10Kaliaperumal Rekha11Saleh A. Ahmed12Muthu Thiruvengadam13Collaborative Innovation Center for Advanced Organic Chemical Materials Co-Constructed by the Province and Ministry, Ministry of Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules and College of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, ChinaMolecular Oncology Laboratory, Department of Biochemistry, Periyar University, Salem 636011, Tamil Nadu, IndiaDepartment of Chemistry, College of Science, Taif University, P.O. Box 110999, Taif 21944, Saudi ArabiaNanotechnology & SRM Research Institute, SRM Institute of Science and Technology, Kattankulathur, Chennai 603203, IndiaNanotechnology & SRM Research Institute, SRM Institute of Science and Technology, Kattankulathur, Chennai 603203, IndiaDepartment of Chemistry, D.K.M. College for Women, Vellore 632001, Tamil Nadu, IndiaDepartment of Epidemic Disease Research, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi ArabiaNational Centre for Biotechnology, King Abdulaziz City for Science and Technology (KACST), P.O. Box 6086, Riyadh 11442, Saudi ArabiaLaboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah P.O. Box 7607, Saudi ArabiaDepartment of Chemistry, Faculty of Applied Sciences, Umm Al-Qura University, Makkah 21955, Saudi ArabiaDepartment of Biomedical Sciences, School of Biosciences and Technology, VIT, Vellore 632014, Tamil Nadu, IndiaDepartment of Environmental and Herbal Science, Tamil University, Thanjavur 613005, Tamil Nadu, IndiaDepartment of Chemistry, Faculty of Applied Sciences, Umm Al-Qura University, Makkah 21955, Saudi ArabiaDepartment of Applied Bioscience, School of Life and Environmental Science, Konkuk University, Seoul 05029, KoreaDue to their appropriate physicochemical properties, nanoparticles are used in nanomedicine to develop drug delivery systems for anticancer therapy. In biomedical applications, metal oxide nanoparticles are used as powerful and flexible multipurpose agents. This work described a green synthesis of Y<sub>2</sub>O<sub>3</sub> nanoparticles (NPs) using the sol-gel technique with the use of aqueous leaf extracts of <i>Lantana camara</i> L (LC). These nanoparticles were characterized with the aid of different methods, including UV, X-ray diffraction (XRD), Fourier transformed infrared spectroscopy (FTIR), transmitted electron microscopy (TEM), and photocatalytic degradation. Y<sub>2</sub>O<sub>3</sub> nanoparticles showed excellent antibacterial activity against Gram-positive <i>Bacillus subtilis</i> and Gram-negative <i>Escherichia coli</i> with a 10 to 15 mm inhibitory zone. Green Y<sub>2</sub>O<sub>3</sub> NPs were released with a 4 h lag time and 80% sustained release rate, indicating that they could be used in drug delivery. In addition, the bioavailability of green Y<sub>2</sub>O<sub>3</sub> NPs was investigated using cell viability in cervical cancer cell lines. These green-synthesized Y<sub>2</sub>O<sub>3</sub> NPs demonstrated photocatalytic degradation, antibacterial, and anticancer properties.https://www.mdpi.com/2079-4991/12/14/2393<i>Lantana camara</i>Y<sub>2</sub>O<sub>3</sub> nanoparticlesphotocatalytic degradationcervical cancerHeLa cells |
| spellingShingle | Rajakumar Govindasamy Mydhili Govindarasu Salman S. Alharthi Preeyanghaa Mani Neppolian Bernaurdshaw Thandapani Gomathi Mohammad Azam Ansari Mohammad N. Alomary Banan Atwah M. Shaheer Malik V. Devi Rajeswari Kaliaperumal Rekha Saleh A. Ahmed Muthu Thiruvengadam Sustainable Green Synthesis of Yttrium Oxide (Y<sub>2</sub>O<sub>3</sub>) Nanoparticles Using <i>Lantana camara</i> Leaf Extracts: Physicochemical Characterization, Photocatalytic Degradation, Antibacterial, and Anticancer Potency Nanomaterials <i>Lantana camara</i> Y<sub>2</sub>O<sub>3</sub> nanoparticles photocatalytic degradation cervical cancer HeLa cells |
| title | Sustainable Green Synthesis of Yttrium Oxide (Y<sub>2</sub>O<sub>3</sub>) Nanoparticles Using <i>Lantana camara</i> Leaf Extracts: Physicochemical Characterization, Photocatalytic Degradation, Antibacterial, and Anticancer Potency |
| title_full | Sustainable Green Synthesis of Yttrium Oxide (Y<sub>2</sub>O<sub>3</sub>) Nanoparticles Using <i>Lantana camara</i> Leaf Extracts: Physicochemical Characterization, Photocatalytic Degradation, Antibacterial, and Anticancer Potency |
| title_fullStr | Sustainable Green Synthesis of Yttrium Oxide (Y<sub>2</sub>O<sub>3</sub>) Nanoparticles Using <i>Lantana camara</i> Leaf Extracts: Physicochemical Characterization, Photocatalytic Degradation, Antibacterial, and Anticancer Potency |
| title_full_unstemmed | Sustainable Green Synthesis of Yttrium Oxide (Y<sub>2</sub>O<sub>3</sub>) Nanoparticles Using <i>Lantana camara</i> Leaf Extracts: Physicochemical Characterization, Photocatalytic Degradation, Antibacterial, and Anticancer Potency |
| title_short | Sustainable Green Synthesis of Yttrium Oxide (Y<sub>2</sub>O<sub>3</sub>) Nanoparticles Using <i>Lantana camara</i> Leaf Extracts: Physicochemical Characterization, Photocatalytic Degradation, Antibacterial, and Anticancer Potency |
| title_sort | sustainable green synthesis of yttrium oxide y sub 2 sub o sub 3 sub nanoparticles using i lantana camara i leaf extracts physicochemical characterization photocatalytic degradation antibacterial and anticancer potency |
| topic | <i>Lantana camara</i> Y<sub>2</sub>O<sub>3</sub> nanoparticles photocatalytic degradation cervical cancer HeLa cells |
| url | https://www.mdpi.com/2079-4991/12/14/2393 |
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