Composition and Applications of Aloe vera Leaf Gel

Many of the health benefits associated with Aloe vera have been attributed to the polysaccharides contained in the gel of the leaves. These biological activities include promotion of wound healing, antifungal activity, hypoglycemic or antidiabetic effects antiinflammatory, anticancer, immunomodulato...

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Main Author: Josias H. Hamman
Format: Article
Language:English
Published: MDPI AG 2008-08-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/13/8/1599/
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author Josias H. Hamman
author_facet Josias H. Hamman
author_sort Josias H. Hamman
collection DOAJ
description Many of the health benefits associated with Aloe vera have been attributed to the polysaccharides contained in the gel of the leaves. These biological activities include promotion of wound healing, antifungal activity, hypoglycemic or antidiabetic effects antiinflammatory, anticancer, immunomodulatory and gastroprotective properties. While the known biological activities of A. vera will be briefly discussed, it is the aim of this review to further highlight recently discovered effects and applications of the leaf gel. These effects include the potential of whole leaf or inner fillet gel liquid preparations of A. vera to enhance the intestinal absorption and bioavailability of co-administered compounds as well as enhancement of skin permeation. In addition, important pharmaceutical applications such as the use of the dried A. vera gel powder as an excipient in sustained release pharmaceutical dosage forms will be outlined.
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spelling doaj.art-f117f86d99c542cbb6a803a5e8717ad02022-12-21T23:47:36ZengMDPI AGMolecules1420-30492008-08-011381599161610.3390/molecules13081599Composition and Applications of Aloe vera Leaf GelJosias H. HammanMany of the health benefits associated with Aloe vera have been attributed to the polysaccharides contained in the gel of the leaves. These biological activities include promotion of wound healing, antifungal activity, hypoglycemic or antidiabetic effects antiinflammatory, anticancer, immunomodulatory and gastroprotective properties. While the known biological activities of A. vera will be briefly discussed, it is the aim of this review to further highlight recently discovered effects and applications of the leaf gel. These effects include the potential of whole leaf or inner fillet gel liquid preparations of A. vera to enhance the intestinal absorption and bioavailability of co-administered compounds as well as enhancement of skin permeation. In addition, important pharmaceutical applications such as the use of the dried A. vera gel powder as an excipient in sustained release pharmaceutical dosage forms will be outlined.http://www.mdpi.com/1420-3049/13/8/1599/Aloe verabiological activitiesabsorption enhancementskin permeationexcipient
spellingShingle Josias H. Hamman
Composition and Applications of Aloe vera Leaf Gel
Molecules
Aloe vera
biological activities
absorption enhancement
skin permeation
excipient
title Composition and Applications of Aloe vera Leaf Gel
title_full Composition and Applications of Aloe vera Leaf Gel
title_fullStr Composition and Applications of Aloe vera Leaf Gel
title_full_unstemmed Composition and Applications of Aloe vera Leaf Gel
title_short Composition and Applications of Aloe vera Leaf Gel
title_sort composition and applications of aloe vera leaf gel
topic Aloe vera
biological activities
absorption enhancement
skin permeation
excipient
url http://www.mdpi.com/1420-3049/13/8/1599/
work_keys_str_mv AT josiashhamman compositionandapplicationsofaloeveraleafgel