A Comparison of Fine Needle Aspiration Biopsy and Excisional Biopsy Results in the Diagnosis of Lymphoma Confined to the Head and Neck Region
Objective: To compare fine needle aspiration biopsy (FNAB) and excisional biopsy results in the diagnosis of head and neck lymphomas and to evaluate the effectiveness of FNAB.Methods: The medical files of 52 patients diagnosed with lymphoma in our clinic between September 2011 and January 2015 were...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2016-12-01
|
| Series: | İstanbul Medical Journal |
| Subjects: | |
| Online Access: |
http://imj.galenos.com.tr/archives/archive-detail/article-preview/a-comparison-of-fine-needle-aspiration-biopsy-and-/20796
|
| _version_ | 1828021424599597056 |
|---|---|
| author | Özlem Önerci Çelebi Yusuf Muhammed Durna Deniz Tuna Edizer Özgür Yiğit Yeşim Karagöz Gülben Erdem Huq |
| author_facet | Özlem Önerci Çelebi Yusuf Muhammed Durna Deniz Tuna Edizer Özgür Yiğit Yeşim Karagöz Gülben Erdem Huq |
| author_sort | Özlem Önerci Çelebi |
| collection | DOAJ |
| description | Objective: To compare fine needle aspiration biopsy (FNAB) and excisional biopsy results in the diagnosis of head and neck lymphomas and to evaluate the effectiveness of FNAB.Methods: The medical files of 52 patients diagnosed with lymphoma in our clinic between September 2011 and January 2015 were retrospectively examined. Demographic characteristics, presenting complaints, hematologic parameters, fine needle aspiration biopsy (FNAB) results, and excisional biopsy results of the patients were recorded. The patients were divided into 4 groups based on their FNAB cytology results: i) malignant cytology, ii) suspicious for lymphoid neoplasia, iii) mixed lymphoid cell population, and iv) non-diagnostic cytology. FNAB was performed under ultrasound guidance.Results: The average age within our series, which consisted of 37 male and 15 female patients, was 46.37 (range 8–82 years). Neck mass was the presenting symptom in 30 patients (57.6%), while it was detected during examination of other symptoms in 22 patients (42.3%). Fever was not observed in any of the patients, whereas weight loss was present in 12 patients (23%), fatigue in 5 patients (9.6%), and night sweats in 5 patients (9.6%). Following excisional biopsy, Hodgkin lymphoma was diagnosed in 28 patients and non-Hodgkin lymphoma was diagnosed in 24 patients.Conclusion: The utility of FNAB in the diagnosis of lymphoma in the head and neck region is discussed. FNAB may not be sufficient unless immunofluorescence examination is also conducted. FNAB may lead to a considerable delay in establishing a definitive diagnosis. In the case of clinical suspicion, excisional biopsy is recommended without performing FNAB. |
| first_indexed | 2024-04-10T11:53:12Z |
| format | Article |
| id | doaj.art-f11d3a6f801045c1bce45b7e290d4909 |
| institution | Directory Open Access Journal |
| issn | 2619-9793 2148-094X |
| language | English |
| last_indexed | 2024-04-10T11:53:12Z |
| publishDate | 2016-12-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | İstanbul Medical Journal |
| spelling | doaj.art-f11d3a6f801045c1bce45b7e290d49092023-02-15T16:17:02ZengGalenos Yayineviİstanbul Medical Journal2619-97932148-094X2016-12-0117411812010.5152/imj.2016.9260913049054A Comparison of Fine Needle Aspiration Biopsy and Excisional Biopsy Results in the Diagnosis of Lymphoma Confined to the Head and Neck RegionÖzlem Önerci Çelebi0Yusuf Muhammed Durna1Deniz Tuna Edizer2Özgür Yiğit3Yeşim Karagöz4Gülben Erdem Huq5 Clinic of Otorhinolaryngology, İstanbul Training and Research Hospital, İstanbul, Türkiye Clinic of Otorhinolaryngology, Lüleburgaz State Hospital, Kırklareli, Türkiye Clinic of Otorhinolaryngology, Bozyaka Training and Research Hospital, İzmir, Türkiye Clinic of Otorhinolaryngology, İstanbul Training and Research Hospital, İstanbul, Türkiye Clinic of Radiology, İstanbul Training and Research Hospital, İstanbul, Türkiye Clinic of Pathology, İstanbul Training and Research Hospital, İstanbul, Türkiye Objective: To compare fine needle aspiration biopsy (FNAB) and excisional biopsy results in the diagnosis of head and neck lymphomas and to evaluate the effectiveness of FNAB.Methods: The medical files of 52 patients diagnosed with lymphoma in our clinic between September 2011 and January 2015 were retrospectively examined. Demographic characteristics, presenting complaints, hematologic parameters, fine needle aspiration biopsy (FNAB) results, and excisional biopsy results of the patients were recorded. The patients were divided into 4 groups based on their FNAB cytology results: i) malignant cytology, ii) suspicious for lymphoid neoplasia, iii) mixed lymphoid cell population, and iv) non-diagnostic cytology. FNAB was performed under ultrasound guidance.Results: The average age within our series, which consisted of 37 male and 15 female patients, was 46.37 (range 8–82 years). Neck mass was the presenting symptom in 30 patients (57.6%), while it was detected during examination of other symptoms in 22 patients (42.3%). Fever was not observed in any of the patients, whereas weight loss was present in 12 patients (23%), fatigue in 5 patients (9.6%), and night sweats in 5 patients (9.6%). Following excisional biopsy, Hodgkin lymphoma was diagnosed in 28 patients and non-Hodgkin lymphoma was diagnosed in 24 patients.Conclusion: The utility of FNAB in the diagnosis of lymphoma in the head and neck region is discussed. FNAB may not be sufficient unless immunofluorescence examination is also conducted. FNAB may lead to a considerable delay in establishing a definitive diagnosis. In the case of clinical suspicion, excisional biopsy is recommended without performing FNAB. http://imj.galenos.com.tr/archives/archive-detail/article-preview/a-comparison-of-fine-needle-aspiration-biopsy-and-/20796 Lymphomafine needle aspiration biopsyexcisional biopsy |
| spellingShingle | Özlem Önerci Çelebi Yusuf Muhammed Durna Deniz Tuna Edizer Özgür Yiğit Yeşim Karagöz Gülben Erdem Huq A Comparison of Fine Needle Aspiration Biopsy and Excisional Biopsy Results in the Diagnosis of Lymphoma Confined to the Head and Neck Region İstanbul Medical Journal Lymphoma fine needle aspiration biopsy excisional biopsy |
| title | A Comparison of Fine Needle Aspiration Biopsy and Excisional Biopsy Results in the Diagnosis of Lymphoma Confined to the Head and Neck Region |
| title_full | A Comparison of Fine Needle Aspiration Biopsy and Excisional Biopsy Results in the Diagnosis of Lymphoma Confined to the Head and Neck Region |
| title_fullStr | A Comparison of Fine Needle Aspiration Biopsy and Excisional Biopsy Results in the Diagnosis of Lymphoma Confined to the Head and Neck Region |
| title_full_unstemmed | A Comparison of Fine Needle Aspiration Biopsy and Excisional Biopsy Results in the Diagnosis of Lymphoma Confined to the Head and Neck Region |
| title_short | A Comparison of Fine Needle Aspiration Biopsy and Excisional Biopsy Results in the Diagnosis of Lymphoma Confined to the Head and Neck Region |
| title_sort | comparison of fine needle aspiration biopsy and excisional biopsy results in the diagnosis of lymphoma confined to the head and neck region |
| topic | Lymphoma fine needle aspiration biopsy excisional biopsy |
| url |
http://imj.galenos.com.tr/archives/archive-detail/article-preview/a-comparison-of-fine-needle-aspiration-biopsy-and-/20796
|
| work_keys_str_mv | AT ozlemonercicelebi acomparisonoffineneedleaspirationbiopsyandexcisionalbiopsyresultsinthediagnosisoflymphomaconfinedtotheheadandneckregion AT yusufmuhammeddurna acomparisonoffineneedleaspirationbiopsyandexcisionalbiopsyresultsinthediagnosisoflymphomaconfinedtotheheadandneckregion AT deniztunaedizer acomparisonoffineneedleaspirationbiopsyandexcisionalbiopsyresultsinthediagnosisoflymphomaconfinedtotheheadandneckregion AT ozguryigit acomparisonoffineneedleaspirationbiopsyandexcisionalbiopsyresultsinthediagnosisoflymphomaconfinedtotheheadandneckregion AT yesimkaragoz acomparisonoffineneedleaspirationbiopsyandexcisionalbiopsyresultsinthediagnosisoflymphomaconfinedtotheheadandneckregion AT gulbenerdemhuq acomparisonoffineneedleaspirationbiopsyandexcisionalbiopsyresultsinthediagnosisoflymphomaconfinedtotheheadandneckregion AT ozlemonercicelebi comparisonoffineneedleaspirationbiopsyandexcisionalbiopsyresultsinthediagnosisoflymphomaconfinedtotheheadandneckregion AT yusufmuhammeddurna comparisonoffineneedleaspirationbiopsyandexcisionalbiopsyresultsinthediagnosisoflymphomaconfinedtotheheadandneckregion AT deniztunaedizer comparisonoffineneedleaspirationbiopsyandexcisionalbiopsyresultsinthediagnosisoflymphomaconfinedtotheheadandneckregion AT ozguryigit comparisonoffineneedleaspirationbiopsyandexcisionalbiopsyresultsinthediagnosisoflymphomaconfinedtotheheadandneckregion AT yesimkaragoz comparisonoffineneedleaspirationbiopsyandexcisionalbiopsyresultsinthediagnosisoflymphomaconfinedtotheheadandneckregion AT gulbenerdemhuq comparisonoffineneedleaspirationbiopsyandexcisionalbiopsyresultsinthediagnosisoflymphomaconfinedtotheheadandneckregion |