Novel read density distribution score shows possible aligner artefacts, when mapping a single chromosome
Abstract Background The use of artificial data to evaluate the performance of aligners and peak callers not only improves its accuracy and reliability, but also makes it possible to reduce the computational time. One of the natural ways to achieve such time reduction is by mapping a single chromosom...
Main Authors: | Fedor M. Naumenko, Irina I. Abnizova, Nathan Beka, Mikhail A. Genaev, Yuriy L. Orlov |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2018-02-01
|
Series: | BMC Genomics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12864-018-4475-6 |
Similar Items
-
Alignment of Short Reads: A Crucial Step for Application of Next-Generation Sequencing Data in Precision Medicine
by: Hao Ye, et al.
Published: (2015-11-01) -
cPlot: Contig-Plotting Visualization for the Analysis of Short-Read Nucleotide Sequence Alignments
by: Mingeun Ji, et al.
Published: (2022-09-01) -
Fast read alignment with incorporation of known genomic variants
by: Hongzhe Guo, et al.
Published: (2019-12-01) -
Scavenger: A pipeline for recovery of unaligned reads utilising similarity with aligned reads [version 2; peer review: 2 approved]
by: Andrian Yang, et al.
Published: (2022-10-01) -
A Review on Sequence Alignment Algorithms for Short Reads Based on Next-Generation Sequencing
by: Jeongkyu Kim, et al.
Published: (2020-01-01)