Mutagenic Consequences of Sublethal Cell Death Signaling

Mutagenic Consequences of Sublethal Cell Death Signaling

Many human cancers exhibit defects in key DNA damage response elements that can render tumors insensitive to the cell death-promoting properties of DNA-damaging therapies. Using agents that directly induce apoptosis by targeting apoptotic components, rather than relying on DNA damage to indirectly s...

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Bibliographic Details
Main Authors: Christine J. Hawkins, Mark A. Miles
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
DNA damage
DNA repair
mutagenesis
apoptosis
necroptosis
ferroptosis
Online Access:https://www.mdpi.com/1422-0067/22/11/6144

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