Characterization of polyacrylamide diblock copolymers by mass spectrometry combined with Mass-remainder analysis (MARA)
Polyacrylamide block copolymers has been extensively used in many fields of science and technology due to their water solubility, biocompatibility and smart and tunable properties. In this study, we used the Mass-remainder analysis (MARA) and the Multi-step Mass-remainder analysis (M-MARA) for the p...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | Polymer Testing |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0142941822003555 |
| _version_ | 1811315931691876352 |
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| author | Tibor Nagy Akos Kuki Gergo Roth Zuura Kaldybek Kyzy Alifya Balqis Zatalini David Nyul Miklos Zsuga Sandor Keki |
| author_facet | Tibor Nagy Akos Kuki Gergo Roth Zuura Kaldybek Kyzy Alifya Balqis Zatalini David Nyul Miklos Zsuga Sandor Keki |
| author_sort | Tibor Nagy |
| collection | DOAJ |
| description | Polyacrylamide block copolymers has been extensively used in many fields of science and technology due to their water solubility, biocompatibility and smart and tunable properties. In this study, we used the Mass-remainder analysis (MARA) and the Multi-step Mass-remainder analysis (M-MARA) for the processing of complex MALDI-TOF mass spectra of a series of poly(N-acryloylmorpholine)-block-poly(N-isopropylacrylamide) diblock copolymers. It was found that selection of the MARA base mass unit affects the shape of the Mass remainder versus m/z plots enabling to draw conclusions about the length and diversity of the blocks. Even better and more informative visualization can be achieved by creating 2-step M-MARA plots. The comprehensive characterization of the poly(N-acryloylmorpholine)-block-poly(N-isopropylacrylamide) copolymers with various block length were performed, and the results were confirmed by nuclear magnetic resonance (NMR) spectroscopy. |
| first_indexed | 2024-04-13T11:40:12Z |
| format | Article |
| id | doaj.art-f1202bf644504211adc0edd2a4881c6f |
| institution | Directory Open Access Journal |
| issn | 0142-9418 |
| language | English |
| last_indexed | 2024-04-13T11:40:12Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Polymer Testing |
| spelling | doaj.art-f1202bf644504211adc0edd2a4881c6f2022-12-22T02:48:20ZengElsevierPolymer Testing0142-94182023-01-01117107834Characterization of polyacrylamide diblock copolymers by mass spectrometry combined with Mass-remainder analysis (MARA)Tibor Nagy0Akos Kuki1Gergo Roth2Zuura Kaldybek Kyzy3Alifya Balqis Zatalini4David Nyul5Miklos Zsuga6Sandor Keki7Department of Applied Chemistry, Faculty of Science and Technology, University of Debrecen, Egyetem tér 1, H-4032, Debrecen, HungaryDepartment of Applied Chemistry, Faculty of Science and Technology, University of Debrecen, Egyetem tér 1, H-4032, Debrecen, HungaryDepartment of Applied Chemistry, Faculty of Science and Technology, University of Debrecen, Egyetem tér 1, H-4032, Debrecen, Hungary; Doctoral School of Chemistry, University of Debrecen, Egyetem tér 1, H-4032, Debrecen, HungaryDepartment of Applied Chemistry, Faculty of Science and Technology, University of Debrecen, Egyetem tér 1, H-4032, Debrecen, HungaryDepartment of Applied Chemistry, Faculty of Science and Technology, University of Debrecen, Egyetem tér 1, H-4032, Debrecen, HungaryDoctoral School of Chemistry, University of Debrecen, Egyetem tér 1, H-4032, Debrecen, Hungary; Department of Physical Chemistry, Faculty of Science and Technology, University of Debrecen, Egyetem tér 1, H-4032, Debrecen, HungaryDepartment of Applied Chemistry, Faculty of Science and Technology, University of Debrecen, Egyetem tér 1, H-4032, Debrecen, HungaryDepartment of Applied Chemistry, Faculty of Science and Technology, University of Debrecen, Egyetem tér 1, H-4032, Debrecen, Hungary; Corresponding Author.Polyacrylamide block copolymers has been extensively used in many fields of science and technology due to their water solubility, biocompatibility and smart and tunable properties. In this study, we used the Mass-remainder analysis (MARA) and the Multi-step Mass-remainder analysis (M-MARA) for the processing of complex MALDI-TOF mass spectra of a series of poly(N-acryloylmorpholine)-block-poly(N-isopropylacrylamide) diblock copolymers. It was found that selection of the MARA base mass unit affects the shape of the Mass remainder versus m/z plots enabling to draw conclusions about the length and diversity of the blocks. Even better and more informative visualization can be achieved by creating 2-step M-MARA plots. The comprehensive characterization of the poly(N-acryloylmorpholine)-block-poly(N-isopropylacrylamide) copolymers with various block length were performed, and the results were confirmed by nuclear magnetic resonance (NMR) spectroscopy.http://www.sciencedirect.com/science/article/pii/S0142941822003555PolyacrylamidesCopolymersMALDI-TOF MSMass-remainder analysis (MARA) |
| spellingShingle | Tibor Nagy Akos Kuki Gergo Roth Zuura Kaldybek Kyzy Alifya Balqis Zatalini David Nyul Miklos Zsuga Sandor Keki Characterization of polyacrylamide diblock copolymers by mass spectrometry combined with Mass-remainder analysis (MARA) Polymer Testing Polyacrylamides Copolymers MALDI-TOF MS Mass-remainder analysis (MARA) |
| title | Characterization of polyacrylamide diblock copolymers by mass spectrometry combined with Mass-remainder analysis (MARA) |
| title_full | Characterization of polyacrylamide diblock copolymers by mass spectrometry combined with Mass-remainder analysis (MARA) |
| title_fullStr | Characterization of polyacrylamide diblock copolymers by mass spectrometry combined with Mass-remainder analysis (MARA) |
| title_full_unstemmed | Characterization of polyacrylamide diblock copolymers by mass spectrometry combined with Mass-remainder analysis (MARA) |
| title_short | Characterization of polyacrylamide diblock copolymers by mass spectrometry combined with Mass-remainder analysis (MARA) |
| title_sort | characterization of polyacrylamide diblock copolymers by mass spectrometry combined with mass remainder analysis mara |
| topic | Polyacrylamides Copolymers MALDI-TOF MS Mass-remainder analysis (MARA) |
| url | http://www.sciencedirect.com/science/article/pii/S0142941822003555 |
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