Semiconducting Polymer Dots for Point-of-Care Biosensing and In Vivo Bioimaging: A Concise Review

In recent years, semiconducting polymer dots (Pdots) have attracted much attention due to their excellent photophysical properties and applicability, such as large absorption cross section, high brightness, tunable fluorescence emission, excellent photostability, good biocompatibility, facile modifi...

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Main Authors: Sile Deng, Lingfeng Li, Jiaxi Zhang, Yongjun Wang, Zhongchao Huang, Haobin Chen
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Biosensors
Subjects:
Online Access:https://www.mdpi.com/2079-6374/13/1/137
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author Sile Deng
Lingfeng Li
Jiaxi Zhang
Yongjun Wang
Zhongchao Huang
Haobin Chen
author_facet Sile Deng
Lingfeng Li
Jiaxi Zhang
Yongjun Wang
Zhongchao Huang
Haobin Chen
author_sort Sile Deng
collection DOAJ
description In recent years, semiconducting polymer dots (Pdots) have attracted much attention due to their excellent photophysical properties and applicability, such as large absorption cross section, high brightness, tunable fluorescence emission, excellent photostability, good biocompatibility, facile modification and regulation. Therefore, Pdots have been widely used in various types of sensing and imaging in biological medicine. More importantly, the recent development of Pdots for point-of-care biosensing and in vivo imaging has emerged as a promising class of optical diagnostic technologies for clinical applications. In this review, we briefly outline strategies for the preparation and modification of Pdots and summarize the recent progress in the development of Pdots-based optical probes for analytical detection and biomedical imaging. Finally, challenges and future developments of Pdots for biomedical applications are given.
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spelling doaj.art-f122bb0ef988427d8535245afa1f92a82023-11-30T21:26:02ZengMDPI AGBiosensors2079-63742023-01-0113113710.3390/bios13010137Semiconducting Polymer Dots for Point-of-Care Biosensing and In Vivo Bioimaging: A Concise ReviewSile Deng0Lingfeng Li1Jiaxi Zhang2Yongjun Wang3Zhongchao Huang4Haobin Chen5Department of Biomedical Engineering, School of Basic Medical Sciences, Central South University, Changsha 410013, ChinaDepartment of Biomedical Engineering, School of Basic Medical Sciences, Central South University, Changsha 410013, ChinaDepartment of Biomedical Engineering, School of Basic Medical Sciences, Central South University, Changsha 410013, ChinaDepartment of Biomedical Engineering, School of Basic Medical Sciences, Central South University, Changsha 410013, ChinaDepartment of Biomedical Engineering, School of Basic Medical Sciences, Central South University, Changsha 410013, ChinaDepartment of Biomedical Engineering, School of Basic Medical Sciences, Central South University, Changsha 410013, ChinaIn recent years, semiconducting polymer dots (Pdots) have attracted much attention due to their excellent photophysical properties and applicability, such as large absorption cross section, high brightness, tunable fluorescence emission, excellent photostability, good biocompatibility, facile modification and regulation. Therefore, Pdots have been widely used in various types of sensing and imaging in biological medicine. More importantly, the recent development of Pdots for point-of-care biosensing and in vivo imaging has emerged as a promising class of optical diagnostic technologies for clinical applications. In this review, we briefly outline strategies for the preparation and modification of Pdots and summarize the recent progress in the development of Pdots-based optical probes for analytical detection and biomedical imaging. Finally, challenges and future developments of Pdots for biomedical applications are given.https://www.mdpi.com/2079-6374/13/1/137polymer dotsbiosensorsfluorescent probessemiconducting polymersmolecular imaging
spellingShingle Sile Deng
Lingfeng Li
Jiaxi Zhang
Yongjun Wang
Zhongchao Huang
Haobin Chen
Semiconducting Polymer Dots for Point-of-Care Biosensing and In Vivo Bioimaging: A Concise Review
Biosensors
polymer dots
biosensors
fluorescent probes
semiconducting polymers
molecular imaging
title Semiconducting Polymer Dots for Point-of-Care Biosensing and In Vivo Bioimaging: A Concise Review
title_full Semiconducting Polymer Dots for Point-of-Care Biosensing and In Vivo Bioimaging: A Concise Review
title_fullStr Semiconducting Polymer Dots for Point-of-Care Biosensing and In Vivo Bioimaging: A Concise Review
title_full_unstemmed Semiconducting Polymer Dots for Point-of-Care Biosensing and In Vivo Bioimaging: A Concise Review
title_short Semiconducting Polymer Dots for Point-of-Care Biosensing and In Vivo Bioimaging: A Concise Review
title_sort semiconducting polymer dots for point of care biosensing and in vivo bioimaging a concise review
topic polymer dots
biosensors
fluorescent probes
semiconducting polymers
molecular imaging
url https://www.mdpi.com/2079-6374/13/1/137
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