PROINFLAMMATORY CYTOKINE PROFILE IN PATIENTS WITH DIFFERENT ALPHA-1-ANTITRYPSIN PHENOTYPES

PROINFLAMMATORY CYTOKINE PROFILE IN PATIENTS WITH DIFFERENT ALPHA-1-ANTITRYPSIN PHENOTYPES

Alpha-1-antitrypsin (A1AT) exerts a wide spectrum of protective effects, being focused on reduction of secondary injury in inflammation. Moreover, A1AT inhibits some serine proteases, and down-regulates production of proinflammatory cytokines. A number of known A1AT phenotypes is accompanied by affe...

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Dettagli Bibliografici
Autori principali: M. Yu. Pervakova, S. V. Lapin, E. A. Surkova, O. Yu. Tkachenko, A. I. Budkova, V. I. Guseva, O. N. Titova, V. L. Emanuel, Areg A. Totolian
Natura: Articolo
Lingua:Russian
Pubblicazione: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2016-12-01
Serie:Медицинская иммунология
Soggetti:
inflammation
alpha-1-antitrypsin
cytokine
alpha-1-antitrypsin phenotype
alpha-1-antitrypsin deficiency
Accesso online:https://www.mimmun.ru/mimmun/article/view/1134

Accesso online

https://www.mimmun.ru/mimmun/article/view/1134

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