Influence of multicomponent plant remedy on the course of experimental dyslipo-proteinemia

The aim of the present study was to assess the antihyperlipidemic and antioxidant effect of multicomponent plant remedy "Atherophyte" in hyperlipidtmic rats. The serum levels of TG, TC, HDL-C, LDL-C, VLDL-C were measured to determine deleterious metabolic effects. The level of MDA was meas...

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Main Authors: T. A. Azhunova, S. V. Lemza
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2015-04-01
Series:Acta Biomedica Scientifica
Subjects:
Online Access:https://www.actabiomedica.ru/jour/article/view/34
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author T. A. Azhunova
S. V. Lemza
author_facet T. A. Azhunova
S. V. Lemza
author_sort T. A. Azhunova
collection DOAJ
description The aim of the present study was to assess the antihyperlipidemic and antioxidant effect of multicomponent plant remedy "Atherophyte" in hyperlipidtmic rats. The serum levels of TG, TC, HDL-C, LDL-C, VLDL-C were measured to determine deleterious metabolic effects. The level of MDA was measured as indicator of free radical activity and catalase activity - as indicator of antioxidant effect of "Atherophyte". After "Atherophyte" administration, the levels of TC, TG, LDL-C and VLDL-C were reduced, the level of HDL-C increased, the level of MDA decreased and CAT activity increased. Thus, the polyphytoextract under study exerts antihyperlipidemic and antioxidant properties.
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2587-9596
language Russian
last_indexed 2024-04-24T17:19:52Z
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spelling doaj.art-f124694636e44d068f58d859871c19a02024-03-28T07:49:14ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962015-04-0102666934Influence of multicomponent plant remedy on the course of experimental dyslipo-proteinemiaT. A. Azhunova0S. V. Lemza1Institute of General and Experimental Biology SB RASInstitute of General and Experimental Biology SB RASThe aim of the present study was to assess the antihyperlipidemic and antioxidant effect of multicomponent plant remedy "Atherophyte" in hyperlipidtmic rats. The serum levels of TG, TC, HDL-C, LDL-C, VLDL-C were measured to determine deleterious metabolic effects. The level of MDA was measured as indicator of free radical activity and catalase activity - as indicator of antioxidant effect of "Atherophyte". After "Atherophyte" administration, the levels of TC, TG, LDL-C and VLDL-C were reduced, the level of HDL-C increased, the level of MDA decreased and CAT activity increased. Thus, the polyphytoextract under study exerts antihyperlipidemic and antioxidant properties.https://www.actabiomedica.ru/jour/article/view/34«атерофит»high-fat dietdyslipoproteinemia“atherophyte"hypolipidemic effect
spellingShingle T. A. Azhunova
S. V. Lemza
Influence of multicomponent plant remedy on the course of experimental dyslipo-proteinemia
Acta Biomedica Scientifica
«атерофит»
high-fat diet
dyslipoproteinemia
“atherophyte"
hypolipidemic effect
title Influence of multicomponent plant remedy on the course of experimental dyslipo-proteinemia
title_full Influence of multicomponent plant remedy on the course of experimental dyslipo-proteinemia
title_fullStr Influence of multicomponent plant remedy on the course of experimental dyslipo-proteinemia
title_full_unstemmed Influence of multicomponent plant remedy on the course of experimental dyslipo-proteinemia
title_short Influence of multicomponent plant remedy on the course of experimental dyslipo-proteinemia
title_sort influence of multicomponent plant remedy on the course of experimental dyslipo proteinemia
topic «атерофит»
high-fat diet
dyslipoproteinemia
“atherophyte"
hypolipidemic effect
url https://www.actabiomedica.ru/jour/article/view/34
work_keys_str_mv AT taazhunova influenceofmulticomponentplantremedyonthecourseofexperimentaldyslipoproteinemia
AT svlemza influenceofmulticomponentplantremedyonthecourseofexperimentaldyslipoproteinemia