Cross-protection induced by highly conserved human B, CD4+, and CD8+ T-cell epitopes-based vaccine against severe infection, disease, and death caused by multiple SARS-CoV-2 variants of concern

Cross-protection induced by highly conserved human B, CD4+, and CD8+ T-cell epitopes-based vaccine against severe infection, disease, and death caused by multiple SARS-CoV-2 variants of concern

BackgroundThe coronavirus disease 2019 (COVID-19) pandemic has created one of the largest global health crises in almost a century. Although the current rate of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections has decreased significantly, the long-term outlook of COVID-19 rema...

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Bibliographic Details
Main Authors: Swayam Prakash, Nisha R. Dhanushkodi, Latifa Zayou, Izabela Coimbra Ibraim, Afshana Quadiri, Pierre Gregoire Coulon, Delia F. Tifrea, Berfin Suzer, Amin Mohammed Shaik, Amruth Chilukuri, Robert A. Edwards, Mahmoud Singer, Hawa Vahed, Anthony B. Nesburn, Baruch D. Kuppermann, Jeffrey B. Ulmer, Daniel Gil, Trevor M. Jones, Lbachir BenMohamed
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
SL-CoVs
COVID-19
vaccine
epitopes
antibodies
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1328905/full

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