| Summary: | The aim of the present study was to investigate the phenolic composition and the biological properties of different <i>Aerva lanata</i> (L). Juss. herb extracts obtained with the use of accelerated solvent extraction (ASE), i.e., a green, ecological method, for cosmetic purposes. All samples exhibited high DPPH<sup>•</sup> (9.17–119.85 mg TE/g) and ABTS<sup>•+</sup> (9.90–107.58 mg TE/g) scavenging activity. The extracts exhibited considerable anti-lipoxygenase (EC<sub>50</sub> between 1.14 mg/mL and 3.73 mg/mL) and anti-xanthine oxidase (EC<sub>50</sub> between 1.28 mg/mL and 3.72 mg/mL) activities, moderate chelating activity (EC<sub>50</sub> between 1.58 mg/mL and 5.30 mg/mL), and high antioxidant potential in the ORAC assay (0.36–3.84 mM TE/g). Changes in the polyphenol profile of the analysed samples depending on the solvent and temperature used for the extraction were determined with the liquid chromatography/electrospray mass spectrometry (LC-ESI-MS/MS) method. Twenty-one phenolic compounds, including flavonoids and phenolic acids, were detected and quantified. It was shown that tiliroside was one of the main phenolic metabolites in the <i>A. lanata</i> (L.) Juss. herb., which may suggest that this compound may be largely responsible for the observed anti-inflammatory activity of the extracts. In addition, the studied extracts exhibited promising skin-related (anti-tyrosinase, anti-elastase, anti-collagenase, and anti-hyaluronidase) activity. This study showed that <i>Aerva lanata</i> (L.) Juss. contains high amounts of phenolic compounds, including tiliroside, and has good skin-related activities. Therefore, the plant may be interesting as a novel source of bioactive agents for cosmetic industries.
|
|---|