Ethnobotanical uses, phytochemistry and biological activity of the genus Euclea: A review
Euclea (Ebenaceae) is a genus of flowering shrubs and trees widely distributed in Africa, the Comoro Islands, and Arabia. This review aimed to evaluate the ethnobotanical uses, phytochemistry, and biological activities of the genus Euclea on available research reports. This was achieved through PubM...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-04-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2023.1170145/full |
| _version_ | 1797844298192912384 |
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| author | Abebe Dagne Taye Gizachew Kassahun Bizuneh Asmamaw Emagn Kasahun |
| author_facet | Abebe Dagne Taye Gizachew Kassahun Bizuneh Asmamaw Emagn Kasahun |
| author_sort | Abebe Dagne Taye |
| collection | DOAJ |
| description | Euclea (Ebenaceae) is a genus of flowering shrubs and trees widely distributed in Africa, the Comoro Islands, and Arabia. This review aimed to evaluate the ethnobotanical uses, phytochemistry, and biological activities of the genus Euclea on available research reports. This was achieved through PubMed, Medline, Google Scholar, Science Direct, Taylor and Francis Online, Wiley Online Library which provides access to scientific and medical research. The extensive literature survey revealed that plants that belong to this genus are used as folkloric medicine for the treatment of diabetes mellitus, toothache, diarrhea, cancer, malaria, leprosy, and genital and oral diseases in the case of HIV/AIDS-related diseases. To date, more than 40 secondary metabolites have been isolated and identified from these plants, especially from E natalensis and E. divinorum. Among these, naphthoquinones, terpenes, and flavonoids are potential secondary metabolites with profound biological activities. Euclea plant extracts and their bioactive compounds possess outstanding pharmacological properties, especially antimalarial, antidiabetic, anticancer, antimicrobial, and antioxidant properties. |
| first_indexed | 2024-04-09T17:20:01Z |
| format | Article |
| id | doaj.art-f12876bf567d4b8888297a1e28e2da03 |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-04-09T17:20:01Z |
| publishDate | 2023-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-f12876bf567d4b8888297a1e28e2da032023-04-19T04:27:10ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122023-04-011410.3389/fphar.2023.11701451170145Ethnobotanical uses, phytochemistry and biological activity of the genus Euclea: A reviewAbebe Dagne Taye0Gizachew Kassahun Bizuneh1Asmamaw Emagn Kasahun2Department of Pharmacy, College of Health Sciences, Debre Markos University, Debre Markos, EthiopiaDepartment of Pharmacognosy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaDepartment of Pharmaceutics, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaEuclea (Ebenaceae) is a genus of flowering shrubs and trees widely distributed in Africa, the Comoro Islands, and Arabia. This review aimed to evaluate the ethnobotanical uses, phytochemistry, and biological activities of the genus Euclea on available research reports. This was achieved through PubMed, Medline, Google Scholar, Science Direct, Taylor and Francis Online, Wiley Online Library which provides access to scientific and medical research. The extensive literature survey revealed that plants that belong to this genus are used as folkloric medicine for the treatment of diabetes mellitus, toothache, diarrhea, cancer, malaria, leprosy, and genital and oral diseases in the case of HIV/AIDS-related diseases. To date, more than 40 secondary metabolites have been isolated and identified from these plants, especially from E natalensis and E. divinorum. Among these, naphthoquinones, terpenes, and flavonoids are potential secondary metabolites with profound biological activities. Euclea plant extracts and their bioactive compounds possess outstanding pharmacological properties, especially antimalarial, antidiabetic, anticancer, antimicrobial, and antioxidant properties.https://www.frontiersin.org/articles/10.3389/fphar.2023.1170145/fullEucleanaphtoquinonesphytochemistryethnobotanical usepharmacological activity |
| spellingShingle | Abebe Dagne Taye Gizachew Kassahun Bizuneh Asmamaw Emagn Kasahun Ethnobotanical uses, phytochemistry and biological activity of the genus Euclea: A review Frontiers in Pharmacology Euclea naphtoquinones phytochemistry ethnobotanical use pharmacological activity |
| title | Ethnobotanical uses, phytochemistry and biological activity of the genus Euclea: A review |
| title_full | Ethnobotanical uses, phytochemistry and biological activity of the genus Euclea: A review |
| title_fullStr | Ethnobotanical uses, phytochemistry and biological activity of the genus Euclea: A review |
| title_full_unstemmed | Ethnobotanical uses, phytochemistry and biological activity of the genus Euclea: A review |
| title_short | Ethnobotanical uses, phytochemistry and biological activity of the genus Euclea: A review |
| title_sort | ethnobotanical uses phytochemistry and biological activity of the genus euclea a review |
| topic | Euclea naphtoquinones phytochemistry ethnobotanical use pharmacological activity |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2023.1170145/full |
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