Automated, High‐Throughput Phenotypic Screening and Analysis Platform to Study Pre‐ and Post‐Implantation Morphogenesis in Stem Cell‐Derived Embryo‐Like Structures

Automated, High‐Throughput Phenotypic Screening and Analysis Platform to Study Pre‐ and Post‐Implantation Morphogenesis in Stem Cell‐Derived Embryo‐Like Structures

Abstract Combining high‐throughput generation and high‐content imaging of embryo models will enable large‐scale screening assays in the fields of (embryo) toxicity, drug development, embryogenesis, and reproductive medicine. This study shows the continuous culture and in situ (i.e., in microwell) im...

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Bibliographic Details
Main Authors: Vinidhra Shankar, Clemens vanBlitterswijk, Erik Vrij, Stefan Giselbrecht
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Advanced Science
Subjects:
bioengineering platform
high‐content imaging
microwells
screening
stem cell‐based embryo models
Online Access:https://doi.org/10.1002/advs.202304987

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