αPIX Is a Trafficking Regulator that Balances Recycling and Degradation of the Epidermal Growth Factor Receptor.

αPIX Is a Trafficking Regulator that Balances Recycling and Degradation of the Epidermal Growth Factor Receptor.

Endosomal sorting is an essential control mechanism for signaling through the epidermal growth factor receptor (EGFR). We report here that the guanine nucleotide exchange factor αPIX, which modulates the activity of Rho-GTPases, is a potent bimodal regulator of EGFR trafficking. αPIX interacts with...

Full description

Bibliographic Details
Main Authors:	Fanny Kortüm, Frederike Leonie Harms, Natascha Hennighausen, Georg Rosenberger
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-01-01
Series:	PLoS ONE
Online Access:	https://doi.org/10.1371/journal.pone.0132737

Similar Items

ZNRF1 Mediates Epidermal Growth Factor Receptor Ubiquitination to Control Receptor Lysosomal Trafficking and Degradation
by: Chia-Hsing Shen, et al.
Published: (2021-04-01)

Analysis of occludin trafficking, demonstrating continuous endocytosis, degradation, recycling and biosynthetic secretory trafficking.
by: Sarah J Fletcher, et al.
Published: (2014-01-01)

Lipocalin-2 Regulates Epidermal Growth Factor Receptor Intracellular Trafficking
by: Lucie Yammine, et al.
Published: (2019-11-01)

Go-Game Image Recognition Based on Improved Pix2pix
by: Yanxia Zheng, et al.
Published: (2023-12-01)

An Enhanced pix2pix Dehazing Network with Guided Filter Layer
by: Qirong Bu, et al.
Published: (2020-08-01)

Isogeometric multi-patch topology optimization based on pix2pix
by: Qingyuan Hu, et al.
Published: (2023-03-01)

Placental Vessel Segmentation Using Pix2pix Compared to U-Net
by: Anouk van der Schot, et al.
Published: (2023-10-01)

Generating Synthetic Images for Healthcare with Novel Deep Pix2Pix GAN
by: Abeer Aljohani, et al.
Published: (2022-10-01)

Nuclear functions and subcellular trafficking mechanisms of the epidermal growth factor receptor family
by: Wang Ying-Nai, et al.
Published: (2012-04-01)

A Radar Reflectivity Image Prediction Method: The Spatial MIM + Pix2Pix
by: Jianlin Guo, et al.
Published: (2023-11-01)

Received signal strength reconstruction using pix2pix generative adversarial network
by: Haochang Wu, et al.
Published: (2023-10-01)

Postoperative corneal topography generation based on attention mechanism and Pix2Pix network
by: Guang-Hua Zhang, et al.
Published: (2023-06-01)

Pix proteins and the evolution of centrioles.
by: Hugh R Woodland, et al.
Published: (2008-01-01)

Role of βPix in the kidney
by: Alexander eStaruschenko, et al.
Published: (2012-05-01)

Fabric Defect Detection Method Using SA-Pix2pix Network and Transfer Learning
by: Feng Hu, et al.
Published: (2023-12-01)

Research on Dispersion Compensation of FD-OCT System via Pix2Pix GAN Technique
by: Eddy Wijanto, et al.
Published: (2024-01-01)

Pix2Pix-Based Monocular Depth Estimation for Drones with Optical Flow on AirSim
by: Tomoyasu Shimada, et al.
Published: (2022-03-01)

A Novel Pix2Pix Enabled Traveling Wave-Based Fault Location Method
by: Jinxian Zhang, et al.
Published: (2021-02-01)

Complex-Valued Pix2pix—Deep Neural Network for Nonlinear Electromagnetic Inverse Scattering
by: Liang Guo, et al.
Published: (2021-03-01)

Pix2Pix Network to Estimate Agricultural Near Infrared Images from RGB Data
by: Daniel Caio de Lima, et al.
Published: (2022-03-01)

An improved pix2pix model based on Gabor filter for robust color image rendering
by: Hong-an Li, et al.
Published: (2022-01-01)

Pix2PixSSR: Spatial super‐resolution synthesis and visualization for time‐varying volumetric data
by: Ji Ma, et al.
Published: (2024-01-01)

PLM-GAN: A Large-Scale Protein Loop Modeling Using pix2pix GAN
by: Mena Nagy A. Khalaf, et al.
Published: (2023-12-01)

Lensless Image Restoration Based on Multi-Stage Deep Neural Networks and Pix2pix Architecture
by: Muyuan Liu, et al.
Published: (2023-11-01)

A Robust InSAR Phase Unwrapping Method via Improving the pix2pix Network
by: Long Zhang, et al.
Published: (2023-10-01)

Impaired degradation followed by enhanced recycling of epidermal growth factor receptor caused by hypo-phosphorylation of tyrosine 1045 in RBE cells
by: Gui Anping, et al.
Published: (2012-05-01)

Activated Protein Kinase C (PKC) Is Persistently Trafficked with Epidermal Growth Factor (EGF) Receptor
by: Carol A. Heckman, et al.
Published: (2020-09-01)

Elemental analysis of proteins by microPIXE.
by: Garman, E, et al.
Published: (2005)

Cisco ASA and PIX firewall handbook /
by: 410629 Hucaby, David
Published: (2005)

Synthetic SAR Data Generator Using Pix2pix cGAN Architecture for Automatic Target Recognition
by: Gustavo F. Araujo, et al.
Published: (2023-01-01)

New Approach Based on Pix2Pix–YOLOv7 mmWave Radar for Target Detection and Classification
by: Mohamed Lamane, et al.
Published: (2023-11-01)

Removing Time Dispersion from Elastic Wave Modeling with the pix2pix Algorithm Based on cGAN
by: Teng Xu, et al.
Published: (2023-06-01)

Synaptic activity regulates AMPA receptor trafficking through different recycling pathways
by: Ning Zheng, et al.
Published: (2015-05-01)

A Method of Enhancing Silk Digital Printing Color Prediction through Pix2Pix GAN-Based Approaches
by: Weijing Zhu, et al.
Published: (2023-12-01)

Cisco ASA, PIX and FWSM firewall handbook /
by: 410629 Hucaby, David, et al.
Published: (2008)

Quantitative Analyses of Urinary Uranium by µ-PIXE
by: Akihiro Uehara, et al.
Published: (2021-01-01)

PIX: explaining a state-owned Fintech
by: Mario G. Schapiro, et al.
Published: (2023-11-01)

Pix2pix Conditional Generative Adversarial Network with MLP Loss Function for Cloud Removal in a Cropland Time Series
by: Luiz E. Christovam, et al.
Published: (2021-12-01)

Remote sensing image analysis and prediction based on improved Pix2Pix model for water environment protection of smart cities
by: Li Wang, et al.
Published: (2023-04-01)

UNC50 prompts G1/S transition and proliferation in HCC by regulation of epidermal growth factor receptor trafficking.
by: Zhou Fang, et al.
Published: (2015-01-01)