Physicochemical analysis of pasteurized human milk and commercial premature formulas fortified with phosphorus solution or commercial fortifier
A study was conducted to determine: the most appropriate proportion (1% or 10% v/v) of a phosphate solution (PS), containing 39mg/mL phosphorus, to be added to pasteurized human milk (HM) or commercial premature formula (FM); the final osmolality of such products, and whether precipitation occurs be...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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São Paulo State University (UNESP)
2009-01-01
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| Series: | Revista de Ciências Farmacêuticas Básica e Aplicada |
| Subjects: | |
| Online Access: | http://rcfba.fcfar.unesp.br/index.php/ojs/article/view/452 |
| _version_ | 1819284859982446592 |
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| author | A.B. Sousa M.C. Sakai C.A. Takagi M. Friedrich |
| author_facet | A.B. Sousa M.C. Sakai C.A. Takagi M. Friedrich |
| author_sort | A.B. Sousa |
| collection | DOAJ |
| description | A study was conducted to determine: the most appropriate proportion (1% or 10% v/v) of a phosphate solution (PS), containing 39mg/mL phosphorus, to be added to pasteurized human milk (HM) or commercial premature formula (FM); the final osmolality of such products, and whether precipitation occurs between calcium (Ca) and phosphorus (P) when commercial fortifier (FOR) or PS is added. A significant increase was observed in the concentrations of Ca in the samples of HM and FM containing FOR and a decrease in the samples of HM containing 10% (v/v) PS. The phosphorus levels increased significantly, in both HM and FM, when FOR or PS (1 and 10%) were added. Osmolality showed a significant increase in the solutions of HM with FOR or 10% PS added, and in the solution of FM containing 10% PS. Qualitative analysis of the precipitate formed on addition of 10% PS to FM revealed that it consisted of dicalcium phosphate. It was concluded that the addition of 10% PS to FM causes a fall in the Ca content, due to its precipitation with phosphate, promoting a reduction in the availability of both ions. On the other hand, the addition of 1% PS was demonstrated to cause no alteration in the Ca concentration, but a significant increase in P. These results suggest that the use of 1% PS is a potential means of supplementation of P after these patients are discharged. |
| first_indexed | 2024-12-24T01:54:05Z |
| format | Article |
| id | doaj.art-f131e04b879041a18d8dca31c7e50264 |
| institution | Directory Open Access Journal |
| issn | 1808-4532 2179-443X |
| language | English |
| last_indexed | 2024-12-24T01:54:05Z |
| publishDate | 2009-01-01 |
| publisher | São Paulo State University (UNESP) |
| record_format | Article |
| series | Revista de Ciências Farmacêuticas Básica e Aplicada |
| spelling | doaj.art-f131e04b879041a18d8dca31c7e502642022-12-21T17:21:38ZengSão Paulo State University (UNESP)Revista de Ciências Farmacêuticas Básica e Aplicada1808-45322179-443X2009-01-01301452Physicochemical analysis of pasteurized human milk and commercial premature formulas fortified with phosphorus solution or commercial fortifierA.B. SousaM.C. SakaiC.A. TakagiM. FriedrichA study was conducted to determine: the most appropriate proportion (1% or 10% v/v) of a phosphate solution (PS), containing 39mg/mL phosphorus, to be added to pasteurized human milk (HM) or commercial premature formula (FM); the final osmolality of such products, and whether precipitation occurs between calcium (Ca) and phosphorus (P) when commercial fortifier (FOR) or PS is added. A significant increase was observed in the concentrations of Ca in the samples of HM and FM containing FOR and a decrease in the samples of HM containing 10% (v/v) PS. The phosphorus levels increased significantly, in both HM and FM, when FOR or PS (1 and 10%) were added. Osmolality showed a significant increase in the solutions of HM with FOR or 10% PS added, and in the solution of FM containing 10% PS. Qualitative analysis of the precipitate formed on addition of 10% PS to FM revealed that it consisted of dicalcium phosphate. It was concluded that the addition of 10% PS to FM causes a fall in the Ca content, due to its precipitation with phosphate, promoting a reduction in the availability of both ions. On the other hand, the addition of 1% PS was demonstrated to cause no alteration in the Ca concentration, but a significant increase in P. These results suggest that the use of 1% PS is a potential means of supplementation of P after these patients are discharged.http://rcfba.fcfar.unesp.br/index.php/ojs/article/view/452pasteurized human milk. commercial premature formulas. phosphorus solution. supplementation. calcium. phosphorus. |
| spellingShingle | A.B. Sousa M.C. Sakai C.A. Takagi M. Friedrich Physicochemical analysis of pasteurized human milk and commercial premature formulas fortified with phosphorus solution or commercial fortifier Revista de Ciências Farmacêuticas Básica e Aplicada pasteurized human milk. commercial premature formulas. phosphorus solution. supplementation. calcium. phosphorus. |
| title | Physicochemical analysis of pasteurized human milk and commercial premature formulas fortified with phosphorus solution or commercial fortifier |
| title_full | Physicochemical analysis of pasteurized human milk and commercial premature formulas fortified with phosphorus solution or commercial fortifier |
| title_fullStr | Physicochemical analysis of pasteurized human milk and commercial premature formulas fortified with phosphorus solution or commercial fortifier |
| title_full_unstemmed | Physicochemical analysis of pasteurized human milk and commercial premature formulas fortified with phosphorus solution or commercial fortifier |
| title_short | Physicochemical analysis of pasteurized human milk and commercial premature formulas fortified with phosphorus solution or commercial fortifier |
| title_sort | physicochemical analysis of pasteurized human milk and commercial premature formulas fortified with phosphorus solution or commercial fortifier |
| topic | pasteurized human milk. commercial premature formulas. phosphorus solution. supplementation. calcium. phosphorus. |
| url | http://rcfba.fcfar.unesp.br/index.php/ojs/article/view/452 |
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