A study on combination of daptomycin with selected antimicrobial agents: in vitro synergistic effect of MIC value of 1 mg/L against MRSA strains

A study on combination of daptomycin with selected antimicrobial agents: in vitro synergistic effect of MIC value of 1 mg/L against MRSA strains

Abstract Background Daptomycin is an important drug used in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infection. A high dose of daptomycin is indicated for an MRSA infection with a minimum inhibitory concentration (MIC) of 1 mg/L for daptomycin. Combination therapies with d...

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Bibliographic Details
Main Authors: Yi-Chien Lee, Pao-Yu Chen, Jann-Tay Wang, Shan-Chwen Chang
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Pharmacology and Toxicology
Subjects:
Combination therapy
Daptomycin
MRSA
Checkerboard assays
Online Access:http://link.springer.com/article/10.1186/s40360-019-0305-y

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