Short interfering RNA inhibits Rift Valley fever virus replication and degradation of protein kinase R in human cells

Short interfering RNA inhibits Rift Valley fever virus replication and degradation of protein kinase R in human cells

Rift Valley fever virus (RVFV) is a mosquito-borne zoonotic pathogen causing severe outbreaks in humans and livestock in sub-Saharan Africa and the Arabian Peninsula. Human infections are characterized by fever, sometimes leading to encephalitis, retinitis, hemorrhagic fever and occasionally death....

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Bibliographic Details
Main Authors: Bonto Faburay, Juergen A Richt
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Microbiology
Subjects:
Rift Valley fever virus
RNA Interference
antiviral
nucleoprotein
Protein kinase r
short interfering RNA
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01889/full

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