Dinoprostone vaginal insert vs the Foley catheter in labor induction. Observational study
Background: A common practice used prior to induction of labor (IOL) is cervical ripening. Currently, there is no consensus from world scientific societies on the method of first choice. One of the most popular method is prostaglandin PGE2 (dinoprostone) usage. It is used in different doses and phar...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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IMR Press
2021-06-01
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| Series: | Clinical and Experimental Obstetrics & Gynecology |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/CEOG/48/3/10.31083/j.ceog.2021.03.2498 |
| _version_ | 1818005946494877696 |
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| author | Jakub Mlodawski Marta Mlodawska Justyna Armanska |
| author_facet | Jakub Mlodawski Marta Mlodawska Justyna Armanska |
| author_sort | Jakub Mlodawski |
| collection | DOAJ |
| description | Background: A common practice used prior to induction of labor (IOL) is cervical ripening. Currently, there is no consensus from world scientific societies on the method of first choice. One of the most popular method is prostaglandin PGE2 (dinoprostone) usage. It is used in different doses and pharmaceutical forms. Methods: In our analysis we compared the obstetrical outcome of IOL using a dinoprostone vaginal insert (DVI) with 10 mg of dinoprostone, which released 0.3 mg/h of dinoprostone for 24 hours (Cervidil®, Ferring Pharmaceutical Poland) with an intracervical Foley catheter (20 F, 50–60 mL balloon). A total of 456 patients (100-DVI, 356-Foley catheter) were included in the study. All patients were in term, singleton pregnancy with intact fetal membranes. Results: In the DVI group, oxytocin was used less frequently during IOL (OR = 0.35, 95% CI 0.23–0.57) and meconium stained amniotic fluid was recorded less often (OR = 0.38, 95% CI = 0.15–0.99). Other obstetric outcomes such as percentage of cesarean deliveries, vaginal operative deliveries, incidence of postpartum haemorrhage, failed labour induction, unreassuring CTG trace did not differ between groups. Clinical condition of newborns and cord blood pH did not differ between groups. In the group of patients pre-induced with a Foley catheter, the need for labor augmentation with oxytocin is more common (62% vs 37%, P < 0.01). Conclusion: Necessity of labor augumentation with oxytocin is more frequent in patients pre-induced with the intracervical Foley catheter compered to DVI usage. There is no difference between groups in obstetrical and neonatological outcomes. |
| first_indexed | 2024-04-14T04:52:36Z |
| format | Article |
| id | doaj.art-f139fbe1541349db982bbd6d01d94af2 |
| institution | Directory Open Access Journal |
| issn | 0390-6663 |
| language | English |
| last_indexed | 2024-04-14T04:52:36Z |
| publishDate | 2021-06-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Clinical and Experimental Obstetrics & Gynecology |
| spelling | doaj.art-f139fbe1541349db982bbd6d01d94af22022-12-22T02:11:14ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632021-06-0148366566910.31083/j.ceog.2021.03.2498S0390-6663(21)00174-3Dinoprostone vaginal insert vs the Foley catheter in labor induction. Observational studyJakub Mlodawski0Marta Mlodawska1Justyna Armanska2Collegium Medicum, Jan Kochanowski University, 25-640 Kielce, PolandCollegium Medicum, Jan Kochanowski University, 25-640 Kielce, PolandClinic of Obstetrics and Gynecology, Provincial Combined Hospital, 25-640 Kielce, PolandBackground: A common practice used prior to induction of labor (IOL) is cervical ripening. Currently, there is no consensus from world scientific societies on the method of first choice. One of the most popular method is prostaglandin PGE2 (dinoprostone) usage. It is used in different doses and pharmaceutical forms. Methods: In our analysis we compared the obstetrical outcome of IOL using a dinoprostone vaginal insert (DVI) with 10 mg of dinoprostone, which released 0.3 mg/h of dinoprostone for 24 hours (Cervidil®, Ferring Pharmaceutical Poland) with an intracervical Foley catheter (20 F, 50–60 mL balloon). A total of 456 patients (100-DVI, 356-Foley catheter) were included in the study. All patients were in term, singleton pregnancy with intact fetal membranes. Results: In the DVI group, oxytocin was used less frequently during IOL (OR = 0.35, 95% CI 0.23–0.57) and meconium stained amniotic fluid was recorded less often (OR = 0.38, 95% CI = 0.15–0.99). Other obstetric outcomes such as percentage of cesarean deliveries, vaginal operative deliveries, incidence of postpartum haemorrhage, failed labour induction, unreassuring CTG trace did not differ between groups. Clinical condition of newborns and cord blood pH did not differ between groups. In the group of patients pre-induced with a Foley catheter, the need for labor augmentation with oxytocin is more common (62% vs 37%, P < 0.01). Conclusion: Necessity of labor augumentation with oxytocin is more frequent in patients pre-induced with the intracervical Foley catheter compered to DVI usage. There is no difference between groups in obstetrical and neonatological outcomes.https://www.imrpress.com/journal/CEOG/48/3/10.31083/j.ceog.2021.03.2498labour inductiondinoprostoneintracervical foley cathetervaginal inserts |
| spellingShingle | Jakub Mlodawski Marta Mlodawska Justyna Armanska Dinoprostone vaginal insert vs the Foley catheter in labor induction. Observational study Clinical and Experimental Obstetrics & Gynecology labour induction dinoprostone intracervical foley catheter vaginal inserts |
| title | Dinoprostone vaginal insert vs the Foley catheter in labor induction. Observational study |
| title_full | Dinoprostone vaginal insert vs the Foley catheter in labor induction. Observational study |
| title_fullStr | Dinoprostone vaginal insert vs the Foley catheter in labor induction. Observational study |
| title_full_unstemmed | Dinoprostone vaginal insert vs the Foley catheter in labor induction. Observational study |
| title_short | Dinoprostone vaginal insert vs the Foley catheter in labor induction. Observational study |
| title_sort | dinoprostone vaginal insert vs the foley catheter in labor induction observational study |
| topic | labour induction dinoprostone intracervical foley catheter vaginal inserts |
| url | https://www.imrpress.com/journal/CEOG/48/3/10.31083/j.ceog.2021.03.2498 |
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