Integrated transcriptomics and metabolomics analysis reveals that C3 and C5 are vital targets of DuZhi Wan in protecting against cerebral ischemic injury
Background/Aims: Duzhi Wan (DZW) has been extensively used in the prevention and treatment of ischemic stroke, but the mechanisms underlying its effects remain unclear. In this study, a combination of transcriptomics, metabolomics and network analysis was applied to identify the preventive mechanism...
Main Authors: | Jing-yi Hou, Guang-zhao Cao, Liang-liang Tian, Rui Zhou, Yi Zhang, He Xu, Hong-wei Wu, Li-fang Wang, Hong-jun Yang, Jing-jing Zhang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-11-01
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Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332222010927 |
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