Efficacy of internet-based cognitive-behavioral therapy for depression in adolescents: A systematic review and meta-analysis
Objective: Internet-based cognitive behavior therapy (ICBT) may provide an accessible alternative to face-to-face treatment, but the evidence base in adolescents is limited. This systematic review and meta-analysis aims to comprehensively assess the efficacy of ICBT in addressing depression among ad...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-12-01
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| Series: | Internet Interventions |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214782923000738 |
| _version_ | 1797405475686318080 |
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| author | Yanan Wu E. Fenfen Yan Wang Meng Xu Simin Liu Liying Zhou Guihang Song Xue Shang Chaoqun Yang Kehu Yang Xiuxia Li |
| author_facet | Yanan Wu E. Fenfen Yan Wang Meng Xu Simin Liu Liying Zhou Guihang Song Xue Shang Chaoqun Yang Kehu Yang Xiuxia Li |
| author_sort | Yanan Wu |
| collection | DOAJ |
| description | Objective: Internet-based cognitive behavior therapy (ICBT) may provide an accessible alternative to face-to-face treatment, but the evidence base in adolescents is limited. This systematic review and meta-analysis aims to comprehensively assess the efficacy of ICBT in addressing depression among adolescents. Methods: Four electronic databases were searched on June 8, 2023. Randomized controlled trials (RCTs) evaluating the efficacy of ICBT for depression in adolescents were included. The quality of the studies was assessed using the risk of bias tool recommended by the Cochrane Handbook. Furthermore, the GRADE approach was employed to gauge the certainty of the obtained evidence. Meta-analysis was conducted using RevMan 5.4, and Egger's test was implemented through Stata for assessment of potential publication bias. Results: A total of 18 RCTs involving 1683 patients were included. In comparison to control groups like attention control, waiting list, and treatment as usual, our meta-analysis findings elucidate a significant reduction in depression scores (SMD = −0.42, 95 % CI: [−0.74, −0.11], p < .05) as well as anxiety scores (SMD = −0.34, 95 % CI: [−0.60, −0.08], p < .05) in adolescents following ICBT interventions. Furthermore, the analysis indicated no notable distinctions in patient's quality of life (QoL) scores. (SMD = 0.12, 95 % CI: [−0.10, 0.34], p > .05). Conclusion: Results provide evidence of the efficacy of ICBT to reduce depressive and anxiety symptoms in adolescents. These research findings are of vital significance for the establishment of evidence-based treatment guidelines in the digital era. Trial registration: PROSPERO registration: CRD42021277562. |
| first_indexed | 2024-03-09T03:10:29Z |
| format | Article |
| id | doaj.art-f1425bf58b4b4ed3abd6c7e2289e2b77 |
| institution | Directory Open Access Journal |
| issn | 2214-7829 |
| language | English |
| last_indexed | 2024-03-09T03:10:29Z |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Internet Interventions |
| spelling | doaj.art-f1425bf58b4b4ed3abd6c7e2289e2b772023-12-04T05:21:58ZengElsevierInternet Interventions2214-78292023-12-0134100673Efficacy of internet-based cognitive-behavioral therapy for depression in adolescents: A systematic review and meta-analysisYanan Wu0E. Fenfen1Yan Wang2Meng Xu3Simin Liu4Liying Zhou5Guihang Song6Xue Shang7Chaoqun Yang8Kehu Yang9Xiuxia Li10Health Technology Assessment Center/Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, China; Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China; Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province, Lanzhou 730000, ChinaQinghai university affiliated hospitalHealth Technology Assessment Center/Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, China; Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China; Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province, Lanzhou 730000, ChinaHealth Technology Assessment Center/Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, China; Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China; Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province, Lanzhou 730000, ChinaHealth Technology Assessment Center/Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, ChinaHealth Technology Assessment Center/Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, China; Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China; Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province, Lanzhou 730000, ChinaHealthcare Security Administration of Gansu Province, Lanzhou 730000, ChinaSchool of Public Health and Emergency Management, Southern University of Science and TechnologyHealth Technology Assessment Center/Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, China; Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China; Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province, Lanzhou 730000, ChinaHealth Technology Assessment Center/Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, China; Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China; Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province, Lanzhou 730000, China; Correspondence to: K. Yang, Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, 199 Donggang West Road, Lanzhou 730000, China.Health Technology Assessment Center/Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, China; Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China; Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province, Lanzhou 730000, China; Correspondence to: X. Li, Health Technology Assessment Center/Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, 199 Donggang West Road, Lanzhou 730000, China.Objective: Internet-based cognitive behavior therapy (ICBT) may provide an accessible alternative to face-to-face treatment, but the evidence base in adolescents is limited. This systematic review and meta-analysis aims to comprehensively assess the efficacy of ICBT in addressing depression among adolescents. Methods: Four electronic databases were searched on June 8, 2023. Randomized controlled trials (RCTs) evaluating the efficacy of ICBT for depression in adolescents were included. The quality of the studies was assessed using the risk of bias tool recommended by the Cochrane Handbook. Furthermore, the GRADE approach was employed to gauge the certainty of the obtained evidence. Meta-analysis was conducted using RevMan 5.4, and Egger's test was implemented through Stata for assessment of potential publication bias. Results: A total of 18 RCTs involving 1683 patients were included. In comparison to control groups like attention control, waiting list, and treatment as usual, our meta-analysis findings elucidate a significant reduction in depression scores (SMD = −0.42, 95 % CI: [−0.74, −0.11], p < .05) as well as anxiety scores (SMD = −0.34, 95 % CI: [−0.60, −0.08], p < .05) in adolescents following ICBT interventions. Furthermore, the analysis indicated no notable distinctions in patient's quality of life (QoL) scores. (SMD = 0.12, 95 % CI: [−0.10, 0.34], p > .05). Conclusion: Results provide evidence of the efficacy of ICBT to reduce depressive and anxiety symptoms in adolescents. These research findings are of vital significance for the establishment of evidence-based treatment guidelines in the digital era. Trial registration: PROSPERO registration: CRD42021277562.http://www.sciencedirect.com/science/article/pii/S2214782923000738Cognitive behavioral therapyInternetDepressionAdolescentsMeta-analysis |
| spellingShingle | Yanan Wu E. Fenfen Yan Wang Meng Xu Simin Liu Liying Zhou Guihang Song Xue Shang Chaoqun Yang Kehu Yang Xiuxia Li Efficacy of internet-based cognitive-behavioral therapy for depression in adolescents: A systematic review and meta-analysis Internet Interventions Cognitive behavioral therapy Internet Depression Adolescents Meta-analysis |
| title | Efficacy of internet-based cognitive-behavioral therapy for depression in adolescents: A systematic review and meta-analysis |
| title_full | Efficacy of internet-based cognitive-behavioral therapy for depression in adolescents: A systematic review and meta-analysis |
| title_fullStr | Efficacy of internet-based cognitive-behavioral therapy for depression in adolescents: A systematic review and meta-analysis |
| title_full_unstemmed | Efficacy of internet-based cognitive-behavioral therapy for depression in adolescents: A systematic review and meta-analysis |
| title_short | Efficacy of internet-based cognitive-behavioral therapy for depression in adolescents: A systematic review and meta-analysis |
| title_sort | efficacy of internet based cognitive behavioral therapy for depression in adolescents a systematic review and meta analysis |
| topic | Cognitive behavioral therapy Internet Depression Adolescents Meta-analysis |
| url | http://www.sciencedirect.com/science/article/pii/S2214782923000738 |
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