Hepatitis-associated aplastic anaemia: a case report from a tertiary care facility of Pakistan
Abstract Hepatitis-associated aplastic anaemia (HAAA) is an uncommon variant of aplastic anaemia which may present as acute or chronic, mild and transient or fulminant disease. The development of aplastic anaemia is usually fatal if not treated in time, with mortality rate being as high as 85%....
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| Format: | Article |
| Language: | English |
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Pakistan Medical Association
2020-11-01
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| Series: | Journal of the Pakistan Medical Association |
| Online Access: | https://www.ojs.jpma.org.pk/index.php/public_html/article/view/2059 |
| _version_ | 1797820625271652352 |
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| author | Laima Alam Sarah Khan |
| author_facet | Laima Alam Sarah Khan |
| author_sort | Laima Alam |
| collection | DOAJ |
| description |
Abstract
Hepatitis-associated aplastic anaemia (HAAA) is an uncommon variant of aplastic anaemia which may present as acute or chronic, mild and transient or fulminant disease. The development of aplastic anaemia is usually fatal if not treated in time, with mortality rate being as high as 85%. A high index of clinical suspicion is required for the diagnosis and exclusion of acquired forms of aplastic anaemia. Here we present a case of a 28-year-old male who presented with sero-negative hepatitis and rapidly progressive bone marrow failure who was given a trial of Granulocyte Colony Stimulating Factor followed by a successful allogenic bone marrow transplant.
Keywords: Hepatitis associated aplastic anaemia, liver injury, bone marrow transplantation. Continuous...
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| first_indexed | 2024-03-13T09:42:01Z |
| format | Article |
| id | doaj.art-f1426b02c1ed4c5b90ec07a632325a7e |
| institution | Directory Open Access Journal |
| issn | 0030-9982 |
| language | English |
| last_indexed | 2024-03-13T09:42:01Z |
| publishDate | 2020-11-01 |
| publisher | Pakistan Medical Association |
| record_format | Article |
| series | Journal of the Pakistan Medical Association |
| spelling | doaj.art-f1426b02c1ed4c5b90ec07a632325a7e2023-05-25T04:24:59ZengPakistan Medical AssociationJournal of the Pakistan Medical Association0030-99822020-11-0110.47391/JPMA.1340Hepatitis-associated aplastic anaemia: a case report from a tertiary care facility of PakistanLaima Alam0Sarah KhanDepartment of Gastroenterology, Pak Emirates Military Hospital, Rawalpindi, Pakistan Abstract Hepatitis-associated aplastic anaemia (HAAA) is an uncommon variant of aplastic anaemia which may present as acute or chronic, mild and transient or fulminant disease. The development of aplastic anaemia is usually fatal if not treated in time, with mortality rate being as high as 85%. A high index of clinical suspicion is required for the diagnosis and exclusion of acquired forms of aplastic anaemia. Here we present a case of a 28-year-old male who presented with sero-negative hepatitis and rapidly progressive bone marrow failure who was given a trial of Granulocyte Colony Stimulating Factor followed by a successful allogenic bone marrow transplant. Keywords: Hepatitis associated aplastic anaemia, liver injury, bone marrow transplantation. Continuous... https://www.ojs.jpma.org.pk/index.php/public_html/article/view/2059 |
| spellingShingle | Laima Alam Sarah Khan Hepatitis-associated aplastic anaemia: a case report from a tertiary care facility of Pakistan Journal of the Pakistan Medical Association |
| title | Hepatitis-associated aplastic anaemia: a case report from a tertiary care facility of Pakistan |
| title_full | Hepatitis-associated aplastic anaemia: a case report from a tertiary care facility of Pakistan |
| title_fullStr | Hepatitis-associated aplastic anaemia: a case report from a tertiary care facility of Pakistan |
| title_full_unstemmed | Hepatitis-associated aplastic anaemia: a case report from a tertiary care facility of Pakistan |
| title_short | Hepatitis-associated aplastic anaemia: a case report from a tertiary care facility of Pakistan |
| title_sort | hepatitis associated aplastic anaemia a case report from a tertiary care facility of pakistan |
| url | https://www.ojs.jpma.org.pk/index.php/public_html/article/view/2059 |
| work_keys_str_mv | AT laimaalam hepatitisassociatedaplasticanaemiaacasereportfromatertiarycarefacilityofpakistan AT sarahkhan hepatitisassociatedaplasticanaemiaacasereportfromatertiarycarefacilityofpakistan |