High-density lipoprotein ameliorates palmitic acid-induced lipotoxicity and oxidative dysfunction in H9c2 cardiomyoblast cells via ROS suppression

High-density lipoprotein ameliorates palmitic acid-induced lipotoxicity and oxidative dysfunction in H9c2 cardiomyoblast cells via ROS suppression

Abstract Background High levels circulating saturated fatty acids are associated with diabetes, obesity and hyperlipidemia. In heart, the accumulation of saturated fatty acids has been determined to play a role in the development of heart failure and diabetic cardiomyopathy. High-density lipoprotein...

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Bibliographic Details
Main Authors: Kuen-Ming Wu, Yuan-Man Hsu, Mei-Chin Ying, Fuu-Jen Tsai, Chang-Hai Tsai, Jing-Gung Chung, Jai-Sing Yang, Chih-Hsin Tang, Li-Yi Cheng, Po-Hua Su, Vijaya Padma Viswanadha, Wei-Wen Kuo, Chih-Yang Huang
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Nutrition & Metabolism
Subjects:
High-density lipoprotein
Palmitic acid
Lipotoxicity
Cardiomyoblast
ROS
Online Access:http://link.springer.com/article/10.1186/s12986-019-0356-5

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