Molecular surveillance reveals a potential hotspot of tick-borne disease in Yakeshi City, Inner Mongolia
Abstract A molecular surveillance of tick-borne diseases was performed in Hulunbuir City, Inner Mongolia. A total of 149 ticks including three species (Ixodes persulcatus, Haemaphysalis concinna, and Dermacentor silvarum) were collected. As many as 11 tick-borne bacterial pathogens were identified i...
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| Format: | Article |
| Language: | English |
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BMC
2023-11-01
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| Series: | BMC Microbiology |
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| Online Access: | https://doi.org/10.1186/s12866-023-03110-6 |
| _version_ | 1797453715150471168 |
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| author | Junhua Tian Jing Liu Hongqing Zhao Xiaomin Chen Xueqin Geng Miao Lu Kun Li |
| author_facet | Junhua Tian Jing Liu Hongqing Zhao Xiaomin Chen Xueqin Geng Miao Lu Kun Li |
| author_sort | Junhua Tian |
| collection | DOAJ |
| description | Abstract A molecular surveillance of tick-borne diseases was performed in Hulunbuir City, Inner Mongolia. A total of 149 ticks including three species (Ixodes persulcatus, Haemaphysalis concinna, and Dermacentor silvarum) were collected. As many as 11 tick-borne bacterial pathogens were identified in them. Some of them have high positive rates. For example, Candidatus Rickettsia tarasevichiae was detected with a high prevalence of 72.48%, while Candidatus Lariskella sp. was detected in 31.54% of ticks. For both Rickettsia raoultii and Anaplasma phagocytophilum, two distinct genotypes were identified based on their phylogenetic trees based on 16S rRNA, gltA, and groEL sequences. Remarkable genetic diversity was also observed for 16S and flaB genes of Borreliella garinii, an agent of Lyme disease. Rickettsia heilongjiangensis causing Far-Eastern spotted fever (2.68%, 4/149), Ehrlichia muris causing human ehrlichiosis (4.70%, 7/149), Borrelia miyamotoi causing relapsing fever (2.01%, 3/149), and Borreliella afzelii causing Lyme disease (2.01%, 3/149) were also detected. Additionally, a previously uncharacterized Anaplasma species closely related to Anaplasma ovis was identified. Herein we name it “Candidatus Anaplasma mongolica”. Based on these results, we propose that Yakeshi City might be a potential hotspot of tick-borne diseases. |
| first_indexed | 2024-03-09T15:26:49Z |
| format | Article |
| id | doaj.art-f1429369f81e4ddeb385a473726620ce |
| institution | Directory Open Access Journal |
| issn | 1471-2180 |
| language | English |
| last_indexed | 2024-03-09T15:26:49Z |
| publishDate | 2023-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Microbiology |
| spelling | doaj.art-f1429369f81e4ddeb385a473726620ce2023-11-26T12:30:17ZengBMCBMC Microbiology1471-21802023-11-0123111010.1186/s12866-023-03110-6Molecular surveillance reveals a potential hotspot of tick-borne disease in Yakeshi City, Inner MongoliaJunhua Tian0Jing Liu1Hongqing Zhao2Xiaomin Chen3Xueqin Geng4Miao Lu5Kun Li6Wuhan Center for Disease Control and PreventionWuhan Center for Disease Control and PreventionNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and PreventionWuhan Center for Disease Control and PreventionCaidian Center for Disease Control and PreventionNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and PreventionNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and PreventionAbstract A molecular surveillance of tick-borne diseases was performed in Hulunbuir City, Inner Mongolia. A total of 149 ticks including three species (Ixodes persulcatus, Haemaphysalis concinna, and Dermacentor silvarum) were collected. As many as 11 tick-borne bacterial pathogens were identified in them. Some of them have high positive rates. For example, Candidatus Rickettsia tarasevichiae was detected with a high prevalence of 72.48%, while Candidatus Lariskella sp. was detected in 31.54% of ticks. For both Rickettsia raoultii and Anaplasma phagocytophilum, two distinct genotypes were identified based on their phylogenetic trees based on 16S rRNA, gltA, and groEL sequences. Remarkable genetic diversity was also observed for 16S and flaB genes of Borreliella garinii, an agent of Lyme disease. Rickettsia heilongjiangensis causing Far-Eastern spotted fever (2.68%, 4/149), Ehrlichia muris causing human ehrlichiosis (4.70%, 7/149), Borrelia miyamotoi causing relapsing fever (2.01%, 3/149), and Borreliella afzelii causing Lyme disease (2.01%, 3/149) were also detected. Additionally, a previously uncharacterized Anaplasma species closely related to Anaplasma ovis was identified. Herein we name it “Candidatus Anaplasma mongolica”. Based on these results, we propose that Yakeshi City might be a potential hotspot of tick-borne diseases.https://doi.org/10.1186/s12866-023-03110-6TicksRickettsiaAnaplasmataceaeBorreliaCandidatus Anaplasma mongolica |
| spellingShingle | Junhua Tian Jing Liu Hongqing Zhao Xiaomin Chen Xueqin Geng Miao Lu Kun Li Molecular surveillance reveals a potential hotspot of tick-borne disease in Yakeshi City, Inner Mongolia BMC Microbiology Ticks Rickettsia Anaplasmataceae Borrelia Candidatus Anaplasma mongolica |
| title | Molecular surveillance reveals a potential hotspot of tick-borne disease in Yakeshi City, Inner Mongolia |
| title_full | Molecular surveillance reveals a potential hotspot of tick-borne disease in Yakeshi City, Inner Mongolia |
| title_fullStr | Molecular surveillance reveals a potential hotspot of tick-borne disease in Yakeshi City, Inner Mongolia |
| title_full_unstemmed | Molecular surveillance reveals a potential hotspot of tick-borne disease in Yakeshi City, Inner Mongolia |
| title_short | Molecular surveillance reveals a potential hotspot of tick-borne disease in Yakeshi City, Inner Mongolia |
| title_sort | molecular surveillance reveals a potential hotspot of tick borne disease in yakeshi city inner mongolia |
| topic | Ticks Rickettsia Anaplasmataceae Borrelia Candidatus Anaplasma mongolica |
| url | https://doi.org/10.1186/s12866-023-03110-6 |
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