Clinical behaviour of ocular surface squamous neoplasia (OSSN) in HIV positive patients
Background: A lot of Ocular Surface Squamous Neoplasia(OSSN) may go unnoticed as they are asymptomatic and usually slow-growing. The prevalence of OSSN is more in tropical region and varies from 12 cases /million/ year in Uganda to 0.3 cases / million/ year in United States of America, possibly rela...
| Główni autorzy: | , , , , |
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| Format: | Artykuł |
| Język: | English |
| Wydane: |
Wolters Kluwer Medknow Publications
2016-01-01
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| Seria: | MRIMS Journal of Health Sciences |
| Hasła przedmiotowe: | |
| Dostęp online: | http://www.mrimsjournal.com/article.asp?issn=2321-7006;year=2016;volume=4;issue=2;spage=114;epage=117;aulast=Padmavathi;type=0 |
| Streszczenie: | Background: A lot of Ocular Surface Squamous Neoplasia(OSSN) may go unnoticed as they are asymptomatic and usually slow-growing. The prevalence of OSSN is more in tropical region and varies from 12 cases /million/ year in Uganda to 0.3 cases / million/ year in United States of America, possibly related to sunlight exposure.
Objective: To study the clinical behaviour of Ocular Surface squamous neoplasia (OSSN) in HIV positive patients.
Methods: This is a retrospective study done at the department of the oculoplastics and orbital diseases, Sarojini Devi Eye Hospital Hyderabad over a period of three years from February 2012 to January 2015. 26 cases of HIV positive patients with OSSN were included in the study and non HIV cases were excluded.
Results: In our study of 26 cases 17 were males and 9 were females and average age of presentation was 34 years 10 to 15 years younger than non HIV cases. Histopathologically 18 cases were squamous cell carcinoma, 5 cases were carcinoma in situ and 3 cases were with moderate to severe dysplasia. Recurrence was seen in 8 cases (32.1%).
Conclusion: OSSN presents at a younger age in HIV positive patients with aggressive behaviour clinically and histopathologically with more chances of recurrence. |
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| ISSN: | 2321-7006 2321-7294 |