Clinical behaviour of ocular surface squamous neoplasia (OSSN) in HIV positive patients
Background: A lot of Ocular Surface Squamous Neoplasia(OSSN) may go unnoticed as they are asymptomatic and usually slow-growing. The prevalence of OSSN is more in tropical region and varies from 12 cases /million/ year in Uganda to 0.3 cases / million/ year in United States of America, possibly rela...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | MRIMS Journal of Health Sciences |
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| Online Access: | http://www.mrimsjournal.com/article.asp?issn=2321-7006;year=2016;volume=4;issue=2;spage=114;epage=117;aulast=Padmavathi;type=0 |
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| author | P Padmavathi D Padma Prabha Mohd. Ather T Kavitha M Padma |
| author_facet | P Padmavathi D Padma Prabha Mohd. Ather T Kavitha M Padma |
| author_sort | P Padmavathi |
| collection | DOAJ |
| description | Background: A lot of Ocular Surface Squamous Neoplasia(OSSN) may go unnoticed as they are asymptomatic and usually slow-growing. The prevalence of OSSN is more in tropical region and varies from 12 cases /million/ year in Uganda to 0.3 cases / million/ year in United States of America, possibly related to sunlight exposure.
Objective: To study the clinical behaviour of Ocular Surface squamous neoplasia (OSSN) in HIV positive patients.
Methods: This is a retrospective study done at the department of the oculoplastics and orbital diseases, Sarojini Devi Eye Hospital Hyderabad over a period of three years from February 2012 to January 2015. 26 cases of HIV positive patients with OSSN were included in the study and non HIV cases were excluded.
Results: In our study of 26 cases 17 were males and 9 were females and average age of presentation was 34 years 10 to 15 years younger than non HIV cases. Histopathologically 18 cases were squamous cell carcinoma, 5 cases were carcinoma in situ and 3 cases were with moderate to severe dysplasia. Recurrence was seen in 8 cases (32.1%).
Conclusion: OSSN presents at a younger age in HIV positive patients with aggressive behaviour clinically and histopathologically with more chances of recurrence. |
| first_indexed | 2024-12-10T22:46:33Z |
| format | Article |
| id | doaj.art-f14375b3ec804577b3925f85d50c5ecf |
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| issn | 2321-7006 2321-7294 |
| language | English |
| last_indexed | 2024-12-10T22:46:33Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | MRIMS Journal of Health Sciences |
| spelling | doaj.art-f14375b3ec804577b3925f85d50c5ecf2022-12-22T01:30:34ZengWolters Kluwer Medknow PublicationsMRIMS Journal of Health Sciences2321-70062321-72942016-01-014211411710.4103/2321-7006.302248Clinical behaviour of ocular surface squamous neoplasia (OSSN) in HIV positive patientsP PadmavathiD Padma PrabhaMohd. AtherT KavithaM PadmaBackground: A lot of Ocular Surface Squamous Neoplasia(OSSN) may go unnoticed as they are asymptomatic and usually slow-growing. The prevalence of OSSN is more in tropical region and varies from 12 cases /million/ year in Uganda to 0.3 cases / million/ year in United States of America, possibly related to sunlight exposure. Objective: To study the clinical behaviour of Ocular Surface squamous neoplasia (OSSN) in HIV positive patients. Methods: This is a retrospective study done at the department of the oculoplastics and orbital diseases, Sarojini Devi Eye Hospital Hyderabad over a period of three years from February 2012 to January 2015. 26 cases of HIV positive patients with OSSN were included in the study and non HIV cases were excluded. Results: In our study of 26 cases 17 were males and 9 were females and average age of presentation was 34 years 10 to 15 years younger than non HIV cases. Histopathologically 18 cases were squamous cell carcinoma, 5 cases were carcinoma in situ and 3 cases were with moderate to severe dysplasia. Recurrence was seen in 8 cases (32.1%). Conclusion: OSSN presents at a younger age in HIV positive patients with aggressive behaviour clinically and histopathologically with more chances of recurrence.http://www.mrimsjournal.com/article.asp?issn=2321-7006;year=2016;volume=4;issue=2;spage=114;epage=117;aulast=Padmavathi;type=0ossn; hiv association; clinical profile; recurrence |
| spellingShingle | P Padmavathi D Padma Prabha Mohd. Ather T Kavitha M Padma Clinical behaviour of ocular surface squamous neoplasia (OSSN) in HIV positive patients MRIMS Journal of Health Sciences ossn; hiv association; clinical profile; recurrence |
| title | Clinical behaviour of ocular surface squamous neoplasia (OSSN) in HIV positive patients |
| title_full | Clinical behaviour of ocular surface squamous neoplasia (OSSN) in HIV positive patients |
| title_fullStr | Clinical behaviour of ocular surface squamous neoplasia (OSSN) in HIV positive patients |
| title_full_unstemmed | Clinical behaviour of ocular surface squamous neoplasia (OSSN) in HIV positive patients |
| title_short | Clinical behaviour of ocular surface squamous neoplasia (OSSN) in HIV positive patients |
| title_sort | clinical behaviour of ocular surface squamous neoplasia ossn in hiv positive patients |
| topic | ossn; hiv association; clinical profile; recurrence |
| url | http://www.mrimsjournal.com/article.asp?issn=2321-7006;year=2016;volume=4;issue=2;spage=114;epage=117;aulast=Padmavathi;type=0 |
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