Debate: "How low should LDL cholesterol be lowered for optimum prevention of vascular disease?" Viewpoint: "Below 100 mg/dl"

<p>Abstract</p> <p>Arteriosclerotic vascular disease manifests as heart disease, stroke, aortic aneurysms, and peripheral vascular disease, and is a growing problem world-wide. The preventive efforts made so far have demonstrated that lowering LDL-C is one action that individuals a...

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Main Author: Brown W Virgil
Format: Article
Language:English
Published: BMC 2001-02-01
Series:Current Controlled Trials in Cardiovascular Medicine
Subjects:
Online Access:http://cvm.controlled-trials.com/content/2/1/012
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author Brown W Virgil
author_facet Brown W Virgil
author_sort Brown W Virgil
collection DOAJ
description <p>Abstract</p> <p>Arteriosclerotic vascular disease manifests as heart disease, stroke, aortic aneurysms, and peripheral vascular disease, and is a growing problem world-wide. The preventive efforts made so far have demonstrated that lowering LDL-C is one action that individuals and populations can do with significant success in delaying the onset of clinical events. Epidemiological studies and small clinical trials suggest that more aggressive and sustained lowering to LDL-C below 100 mg/dl could result in 50 to 70% reductions in vascular death. The full benefit of reducing LDL-C is only now being tested in adequate clinical trials.</p>
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spelling doaj.art-f145186fd165493193a81f5c9d5dd3962022-12-21T23:30:44ZengBMCCurrent Controlled Trials in Cardiovascular Medicine1468-67082001-02-0121121510.1186/cvm-2-1-012Debate: "How low should LDL cholesterol be lowered for optimum prevention of vascular disease?" Viewpoint: "Below 100 mg/dl"Brown W Virgil<p>Abstract</p> <p>Arteriosclerotic vascular disease manifests as heart disease, stroke, aortic aneurysms, and peripheral vascular disease, and is a growing problem world-wide. The preventive efforts made so far have demonstrated that lowering LDL-C is one action that individuals and populations can do with significant success in delaying the onset of clinical events. Epidemiological studies and small clinical trials suggest that more aggressive and sustained lowering to LDL-C below 100 mg/dl could result in 50 to 70% reductions in vascular death. The full benefit of reducing LDL-C is only now being tested in adequate clinical trials.</p>http://cvm.controlled-trials.com/content/2/1/012arteriosclerosischolesterolclinical trialsLDLvascular disease
spellingShingle Brown W Virgil
Debate: "How low should LDL cholesterol be lowered for optimum prevention of vascular disease?" Viewpoint: "Below 100 mg/dl"
Current Controlled Trials in Cardiovascular Medicine
arteriosclerosis
cholesterol
clinical trials
LDL
vascular disease
title Debate: "How low should LDL cholesterol be lowered for optimum prevention of vascular disease?" Viewpoint: "Below 100 mg/dl"
title_full Debate: "How low should LDL cholesterol be lowered for optimum prevention of vascular disease?" Viewpoint: "Below 100 mg/dl"
title_fullStr Debate: "How low should LDL cholesterol be lowered for optimum prevention of vascular disease?" Viewpoint: "Below 100 mg/dl"
title_full_unstemmed Debate: "How low should LDL cholesterol be lowered for optimum prevention of vascular disease?" Viewpoint: "Below 100 mg/dl"
title_short Debate: "How low should LDL cholesterol be lowered for optimum prevention of vascular disease?" Viewpoint: "Below 100 mg/dl"
title_sort debate how low should ldl cholesterol be lowered for optimum prevention of vascular disease viewpoint below 100 mg dl
topic arteriosclerosis
cholesterol
clinical trials
LDL
vascular disease
url http://cvm.controlled-trials.com/content/2/1/012
work_keys_str_mv AT brownwvirgil debatehowlowshouldldlcholesterolbeloweredforoptimumpreventionofvasculardiseaseviewpointbelow100mgdl