Enhanced inter-compartmental Ca2+ flux modulates mitochondrial metabolism and apoptotic threshold during aging
Background: Senescence is characterized by a gradual decline in cellular functions, including changes in energy homeostasis and decreased proliferation activity. As cellular power plants, contributors to signal transduction, sources of reactive oxygen species (ROS) and executors of programmed cell d...
Main Authors: | Corina T. Madreiter-Sokolowski, Markus Waldeck-Weiermair, Marie-Pierre Bourguignon, Nicole Villeneuve, Benjamin Gottschalk, Christiane Klec, Sarah Stryeck, Snjezana Radulovic, Warisara Parichatikanond, Saša Frank, Tobias Madl, Roland Malli, Wolfgang F. Graier |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-01-01
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Series: | Redox Biology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231718309479 |
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