Enhanced inter-compartmental Ca2+ flux modulates mitochondrial metabolism and apoptotic threshold during aging

Background: Senescence is characterized by a gradual decline in cellular functions, including changes in energy homeostasis and decreased proliferation activity. As cellular power plants, contributors to signal transduction, sources of reactive oxygen species (ROS) and executors of programmed cell d...

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Bibliographic Details
Main Authors: Corina T. Madreiter-Sokolowski, Markus Waldeck-Weiermair, Marie-Pierre Bourguignon, Nicole Villeneuve, Benjamin Gottschalk, Christiane Klec, Sarah Stryeck, Snjezana Radulovic, Warisara Parichatikanond, Saša Frank, Tobias Madl, Roland Malli, Wolfgang F. Graier
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718309479

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