Autopsy case of a patient with rapidly progressive combined small‐cell lung carcinoma with spindle‐shaped cell tumor
Abstract A 69‐year‐old Japanese man visited our hospital because of worsening shortness of breath. His chest computed tomography (CT) showed a giant left lung mass with a massive left pleural effusion. He could not be treated with chemotherapy and eventually died from a rapidly progressive tumor. He...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-08-01
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| Series: | Thoracic Cancer |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/1759-7714.14559 |
| _version_ | 1811343178570137600 |
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| author | Toshiki Morimoto Kei Yamasaki Tatsuya Shingu Tomoki Sato Takumu Uryu Takanobu Jotatsu Kaori Kato Hiroki Kawabata Chinatsu Nishida Kazuhiro Yatera |
| author_facet | Toshiki Morimoto Kei Yamasaki Tatsuya Shingu Tomoki Sato Takumu Uryu Takanobu Jotatsu Kaori Kato Hiroki Kawabata Chinatsu Nishida Kazuhiro Yatera |
| author_sort | Toshiki Morimoto |
| collection | DOAJ |
| description | Abstract A 69‐year‐old Japanese man visited our hospital because of worsening shortness of breath. His chest computed tomography (CT) showed a giant left lung mass with a massive left pleural effusion. He could not be treated with chemotherapy and eventually died from a rapidly progressive tumor. He was diagnosed with combined small cell lung carcinoma (C‐SCLC) with spindle‐shaped cell tumor at autopsy. C‐SCLC is characterized by pathologically concurrent SCLC and adenocarcinoma or squamous cell carcinoma, or rarely, spindle‐shaped cell tumor. The clinical course of C‐SCLC with spindle‐shaped cell tumor has not previously been determined. Our patient's tumor increased by 2.59‐fold in 20 days. The combination of C‐SCLC with spindle‐shaped cell tumor suggested rapid progression and a poor prognosis. |
| first_indexed | 2024-04-13T19:24:02Z |
| format | Article |
| id | doaj.art-f145977521cd4f47ae32968eec2edad5 |
| institution | Directory Open Access Journal |
| issn | 1759-7706 1759-7714 |
| language | English |
| last_indexed | 2024-04-13T19:24:02Z |
| publishDate | 2022-08-01 |
| publisher | Wiley |
| record_format | Article |
| series | Thoracic Cancer |
| spelling | doaj.art-f145977521cd4f47ae32968eec2edad52022-12-22T02:33:25ZengWileyThoracic Cancer1759-77061759-77142022-08-0113152279228210.1111/1759-7714.14559Autopsy case of a patient with rapidly progressive combined small‐cell lung carcinoma with spindle‐shaped cell tumorToshiki Morimoto0Kei Yamasaki1Tatsuya Shingu2Tomoki Sato3Takumu Uryu4Takanobu Jotatsu5Kaori Kato6Hiroki Kawabata7Chinatsu Nishida8Kazuhiro Yatera9Department of Respiratory Medicine University of Occupational and Environmental Health Kitakyushu City JapanDepartment of Respiratory Medicine University of Occupational and Environmental Health Kitakyushu City JapanDepartment of Respiratory Medicine University of Occupational and Environmental Health Kitakyushu City JapanDepartment of Respiratory Medicine University of Occupational and Environmental Health Kitakyushu City JapanDepartment of Respiratory Medicine University of Occupational and Environmental Health Kitakyushu City JapanDepartment of Respiratory Medicine University of Occupational and Environmental Health Kitakyushu City JapanDepartment of Respiratory Medicine University of Occupational and Environmental Health Kitakyushu City JapanDepartment of Respiratory Medicine University of Occupational and Environmental Health Kitakyushu City JapanDepartment of Respiratory Medicine University of Occupational and Environmental Health Kitakyushu City JapanDepartment of Respiratory Medicine University of Occupational and Environmental Health Kitakyushu City JapanAbstract A 69‐year‐old Japanese man visited our hospital because of worsening shortness of breath. His chest computed tomography (CT) showed a giant left lung mass with a massive left pleural effusion. He could not be treated with chemotherapy and eventually died from a rapidly progressive tumor. He was diagnosed with combined small cell lung carcinoma (C‐SCLC) with spindle‐shaped cell tumor at autopsy. C‐SCLC is characterized by pathologically concurrent SCLC and adenocarcinoma or squamous cell carcinoma, or rarely, spindle‐shaped cell tumor. The clinical course of C‐SCLC with spindle‐shaped cell tumor has not previously been determined. Our patient's tumor increased by 2.59‐fold in 20 days. The combination of C‐SCLC with spindle‐shaped cell tumor suggested rapid progression and a poor prognosis.https://doi.org/10.1111/1759-7714.14559adenocarcinomacombined small‐cell lung carcinomaspindle‐shaped cell tumor |
| spellingShingle | Toshiki Morimoto Kei Yamasaki Tatsuya Shingu Tomoki Sato Takumu Uryu Takanobu Jotatsu Kaori Kato Hiroki Kawabata Chinatsu Nishida Kazuhiro Yatera Autopsy case of a patient with rapidly progressive combined small‐cell lung carcinoma with spindle‐shaped cell tumor Thoracic Cancer adenocarcinoma combined small‐cell lung carcinoma spindle‐shaped cell tumor |
| title | Autopsy case of a patient with rapidly progressive combined small‐cell lung carcinoma with spindle‐shaped cell tumor |
| title_full | Autopsy case of a patient with rapidly progressive combined small‐cell lung carcinoma with spindle‐shaped cell tumor |
| title_fullStr | Autopsy case of a patient with rapidly progressive combined small‐cell lung carcinoma with spindle‐shaped cell tumor |
| title_full_unstemmed | Autopsy case of a patient with rapidly progressive combined small‐cell lung carcinoma with spindle‐shaped cell tumor |
| title_short | Autopsy case of a patient with rapidly progressive combined small‐cell lung carcinoma with spindle‐shaped cell tumor |
| title_sort | autopsy case of a patient with rapidly progressive combined small cell lung carcinoma with spindle shaped cell tumor |
| topic | adenocarcinoma combined small‐cell lung carcinoma spindle‐shaped cell tumor |
| url | https://doi.org/10.1111/1759-7714.14559 |
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