| Summary: | Background: Determine predictors of early diagnosis and prevalence of OHS among patient with sleep disordered breathing (SDB) at Mansoura SDB unit.
Aim of work: Determine predictors of early diagnosis and prevalence of OHS among patient with sleep disordered breathing (SDB) diagnosed at Mansoura SDB unit.
Patients and methods: The study population consists of 212 patients referred to Mansoura University SDB unit for investigation of possible SDB. All patients were subjected to the following: Clinical evaluation, Pulse oximeter, Erect awake ABG, Spirometry and Polysomnography.
Results: It was found that; The overall prevalence of OHS in studied cases was 13.2% (28 out of 212) and the prevalence of SDB in all studied cases was 83.02% (176 out of 212), 15.91% (28 out of 176) with OHS. The following predictors can be used for early diagnosis of OHS; a cutoff point of 93% of erect awake SpO2 with sensitivity of 97.1%, Specificity of 100%, p < 0.001, a cutoff point of 28 mmol/dL of serum HCO3 with sensitivity of 85.7%, specificity of 95.6%, p < 0.001, and a cutoff point of 46.40 of AHI with sensitivity of 78.6%, specificity of 77.9 p = 0.001.
Conclusion: The prevalence of OHS among patients with SDB diagnosed at Mansoura SDB unit was 15.91% and 16.67% among obese patients with SDB. The following cutoff points can be used as promising predictors for early diagnosis of OHS: Erect awake SpO2 < 93%, Serum HCO3 > 28 mmol/L and AHI > 46.4.
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