Functions of glutaminyl cyclase and its isoform in diseases

Functions of glutaminyl cyclase and its isoform in diseases

Glutaminyl cyclase (QC; isoform: isoQC) is a zinc-dependent enzyme that catalyzes the intramolecular cyclization of N-terminal glutamine and glutamic acid residues into a pyroglutamate residue (pGlu). This conversion is a type of posttranslational modification called pyroglutamylation. The expressio...

Full description

Bibliographic Details
Main Authors: Liu Yu’e, Shi Yufeng, Wang Ping
Format: Article
Language:English
Published: EDP Sciences 2023-01-01
Series:Visualized Cancer Medicine
Subjects:
glutaminyl cyclase
qpctl
pyroglutamylation
phagocytosis
cd47
isoqc
Online Access:https://vcm.edpsciences.org/articles/vcm/full_html/2023/01/vcm20220009/vcm20220009.html

Similar Items

Similar Items