Evidence-Based Mechanical Ventilatory Strategies in ARDS
Acute respiratory distress syndrome (ARDS) remains one of the leading causes of morbidity and mortality in critically ill patients despite advancements in the field. Mechanical ventilatory strategies are a vital component of ARDS management to prevent secondary lung injury and improve patient outcom...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-01-01
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| Series: | Journal of Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0383/11/2/319 |
| _version_ | 1797493067830263808 |
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| author | Adnan Liaqat Matthew Mason Brian J. Foster Sagar Kulkarni Aisha Barlas Awais M. Farooq Pooja Patak Hamza Liaqat Rafaela G. Basso Mohammed S. Zaman Dhaval Pau |
| author_facet | Adnan Liaqat Matthew Mason Brian J. Foster Sagar Kulkarni Aisha Barlas Awais M. Farooq Pooja Patak Hamza Liaqat Rafaela G. Basso Mohammed S. Zaman Dhaval Pau |
| author_sort | Adnan Liaqat |
| collection | DOAJ |
| description | Acute respiratory distress syndrome (ARDS) remains one of the leading causes of morbidity and mortality in critically ill patients despite advancements in the field. Mechanical ventilatory strategies are a vital component of ARDS management to prevent secondary lung injury and improve patient outcomes. Multiple strategies including utilization of low tidal volumes, targeting low plateau pressures to minimize barotrauma, using low FiO<sub>2</sub> (fraction of inspired oxygen) to prevent injury related to oxygen free radicals, optimization of positive end expiratory pressure (PEEP) to maintain or improve lung recruitment, and utilization of prone ventilation have been shown to decrease morbidity and mortality. The role of other mechanical ventilatory strategies like non-invasive ventilation, recruitment maneuvers, esophageal pressure monitoring, determination of optimal PEEP, and appropriate patient selection for extracorporeal support is not clear. In this article, we review evidence-based mechanical ventilatory strategies and ventilatory adjuncts for ARDS. |
| first_indexed | 2024-03-10T01:14:41Z |
| format | Article |
| id | doaj.art-f14a1132860f4a70840bff106df52114 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T01:14:41Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-f14a1132860f4a70840bff106df521142023-11-23T14:11:59ZengMDPI AGJournal of Clinical Medicine2077-03832022-01-0111231910.3390/jcm11020319Evidence-Based Mechanical Ventilatory Strategies in ARDSAdnan Liaqat0Matthew Mason1Brian J. Foster2Sagar Kulkarni3Aisha Barlas4Awais M. Farooq5Pooja Patak6Hamza Liaqat7Rafaela G. Basso8Mohammed S. Zaman9Dhaval Pau10Southeast Health, Dothan, AL 36301, USAAlabama College of Osteopathic Medicine, Dothan, AL 36303, USASoutheast Health, Dothan, AL 36301, USASoutheast Health, Dothan, AL 36301, USAMercy Health, Rockford, IL 61114, USASoutheast Health, Dothan, AL 36301, USASoutheast Health, Dothan, AL 36301, USAWah Medical College, Wah Cantt 47040, PakistanSoutheast Health, Dothan, AL 36301, USASoutheast Health, Dothan, AL 36301, USASoutheast Health, Dothan, AL 36301, USAAcute respiratory distress syndrome (ARDS) remains one of the leading causes of morbidity and mortality in critically ill patients despite advancements in the field. Mechanical ventilatory strategies are a vital component of ARDS management to prevent secondary lung injury and improve patient outcomes. Multiple strategies including utilization of low tidal volumes, targeting low plateau pressures to minimize barotrauma, using low FiO<sub>2</sub> (fraction of inspired oxygen) to prevent injury related to oxygen free radicals, optimization of positive end expiratory pressure (PEEP) to maintain or improve lung recruitment, and utilization of prone ventilation have been shown to decrease morbidity and mortality. The role of other mechanical ventilatory strategies like non-invasive ventilation, recruitment maneuvers, esophageal pressure monitoring, determination of optimal PEEP, and appropriate patient selection for extracorporeal support is not clear. In this article, we review evidence-based mechanical ventilatory strategies and ventilatory adjuncts for ARDS.https://www.mdpi.com/2077-0383/11/2/319acute respiratory distress syndromeARDSmechanical ventilation strategiesPEEPlung recruitmentnoninvasive ventilation |
| spellingShingle | Adnan Liaqat Matthew Mason Brian J. Foster Sagar Kulkarni Aisha Barlas Awais M. Farooq Pooja Patak Hamza Liaqat Rafaela G. Basso Mohammed S. Zaman Dhaval Pau Evidence-Based Mechanical Ventilatory Strategies in ARDS Journal of Clinical Medicine acute respiratory distress syndrome ARDS mechanical ventilation strategies PEEP lung recruitment noninvasive ventilation |
| title | Evidence-Based Mechanical Ventilatory Strategies in ARDS |
| title_full | Evidence-Based Mechanical Ventilatory Strategies in ARDS |
| title_fullStr | Evidence-Based Mechanical Ventilatory Strategies in ARDS |
| title_full_unstemmed | Evidence-Based Mechanical Ventilatory Strategies in ARDS |
| title_short | Evidence-Based Mechanical Ventilatory Strategies in ARDS |
| title_sort | evidence based mechanical ventilatory strategies in ards |
| topic | acute respiratory distress syndrome ARDS mechanical ventilation strategies PEEP lung recruitment noninvasive ventilation |
| url | https://www.mdpi.com/2077-0383/11/2/319 |
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