Microdosimetry performance of the first multi-arrays of 3D-cylindrical microdetectors
Abstract The present work reports on the microdosimetry measurements performed with the two first multi-arrays of microdosimeters with the highest radiation sensitive surface covered so far. The sensors are based on new silicon-based radiation detectors with a novel 3D cylindrical architecture. Each...
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| Format: | Article |
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Nature Portfolio
2022-07-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-14940-1 |
| _version_ | 1811287151235563520 |
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| author | Diana Bachiller-Perea Mingming Zhang Celeste Fleta David Quirion Daniela Bassignana Faustino Gómez Consuelo Guardiola |
| author_facet | Diana Bachiller-Perea Mingming Zhang Celeste Fleta David Quirion Daniela Bassignana Faustino Gómez Consuelo Guardiola |
| author_sort | Diana Bachiller-Perea |
| collection | DOAJ |
| description | Abstract The present work reports on the microdosimetry measurements performed with the two first multi-arrays of microdosimeters with the highest radiation sensitive surface covered so far. The sensors are based on new silicon-based radiation detectors with a novel 3D cylindrical architecture. Each system consists of arrays of independent microdetectors covering 2 mm $$\times$$ × 2 mm and 0.4 mm $$\times$$ × 12 cm radiation sensitive areas, the sensor distributions are arranged in layouts of 11 $$\times$$ × 11 microdetectors and 3 $$\times$$ × 3 multi-arrays, respectively. We have performed proton irradiations at several energies to compare the microdosimetry performance of the two systems, which have different spatial resolution and detection surface. The unitcell of both arrays is a 3D cylindrical diode with a 25 $$\mu$$ μ m diameter and a 20 $$\mu$$ μ m depth that results in a welldefined and isolated radiation sensitive micro-volume etched inside a silicon wafer. Measurements were carried out at the Accélérateur Linéaire et Tandem à Orsay (ALTO) facility by irradiating the two detection systems with monoenergetic proton beams from 6 to 20 MeV at clinical-equivalent fluence rates. The microdosimetry quantities were obtained with a spatial resolution of 200 $$\mu$$ μ m and 600 $$\mu$$ μ m for the 11 $$\times$$ × 11 system and for the 3 $$\times$$ × 3 multi-array system, respectively. Experimental results were compared with Monte Carlo simulations and an overall good agreement was found. The good performance of both microdetector arrays demonstrates that this architecture and both configurations can be used clinically as microdosimeters for measuring the lineal energy distributions and, thus, for RBE optimization of hadron therapy treatments. Likewise, the results have shown that the devices can be also employed as a multipurpose device for beam monitoring in particle accelerators. |
| first_indexed | 2024-04-13T03:13:39Z |
| format | Article |
| id | doaj.art-f14d1c8f5c124a658b407c04bac25916 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-13T03:13:39Z |
| publishDate | 2022-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-f14d1c8f5c124a658b407c04bac259162022-12-22T03:04:59ZengNature PortfolioScientific Reports2045-23222022-07-0112111510.1038/s41598-022-14940-1Microdosimetry performance of the first multi-arrays of 3D-cylindrical microdetectorsDiana Bachiller-Perea0Mingming Zhang1Celeste Fleta2David Quirion3Daniela Bassignana4Faustino Gómez5Consuelo Guardiola6Université Paris-Saclay, CNRS/IN2P3, IJCLabUniversité Paris-Saclay, CNRS/IN2P3, IJCLabInstituto de Microelectrónica de Barcelona (IMB-CNM, CSIC)Instituto de Microelectrónica de Barcelona (IMB-CNM, CSIC)Instituto de Microelectrónica de Barcelona (IMB-CNM, CSIC)Departamento de Física de Partículas, Universidad de Santiago de CompostelaUniversité Paris-Saclay, CNRS/IN2P3, IJCLabAbstract The present work reports on the microdosimetry measurements performed with the two first multi-arrays of microdosimeters with the highest radiation sensitive surface covered so far. The sensors are based on new silicon-based radiation detectors with a novel 3D cylindrical architecture. Each system consists of arrays of independent microdetectors covering 2 mm $$\times$$ × 2 mm and 0.4 mm $$\times$$ × 12 cm radiation sensitive areas, the sensor distributions are arranged in layouts of 11 $$\times$$ × 11 microdetectors and 3 $$\times$$ × 3 multi-arrays, respectively. We have performed proton irradiations at several energies to compare the microdosimetry performance of the two systems, which have different spatial resolution and detection surface. The unitcell of both arrays is a 3D cylindrical diode with a 25 $$\mu$$ μ m diameter and a 20 $$\mu$$ μ m depth that results in a welldefined and isolated radiation sensitive micro-volume etched inside a silicon wafer. Measurements were carried out at the Accélérateur Linéaire et Tandem à Orsay (ALTO) facility by irradiating the two detection systems with monoenergetic proton beams from 6 to 20 MeV at clinical-equivalent fluence rates. The microdosimetry quantities were obtained with a spatial resolution of 200 $$\mu$$ μ m and 600 $$\mu$$ μ m for the 11 $$\times$$ × 11 system and for the 3 $$\times$$ × 3 multi-array system, respectively. Experimental results were compared with Monte Carlo simulations and an overall good agreement was found. The good performance of both microdetector arrays demonstrates that this architecture and both configurations can be used clinically as microdosimeters for measuring the lineal energy distributions and, thus, for RBE optimization of hadron therapy treatments. Likewise, the results have shown that the devices can be also employed as a multipurpose device for beam monitoring in particle accelerators.https://doi.org/10.1038/s41598-022-14940-1 |
| spellingShingle | Diana Bachiller-Perea Mingming Zhang Celeste Fleta David Quirion Daniela Bassignana Faustino Gómez Consuelo Guardiola Microdosimetry performance of the first multi-arrays of 3D-cylindrical microdetectors Scientific Reports |
| title | Microdosimetry performance of the first multi-arrays of 3D-cylindrical microdetectors |
| title_full | Microdosimetry performance of the first multi-arrays of 3D-cylindrical microdetectors |
| title_fullStr | Microdosimetry performance of the first multi-arrays of 3D-cylindrical microdetectors |
| title_full_unstemmed | Microdosimetry performance of the first multi-arrays of 3D-cylindrical microdetectors |
| title_short | Microdosimetry performance of the first multi-arrays of 3D-cylindrical microdetectors |
| title_sort | microdosimetry performance of the first multi arrays of 3d cylindrical microdetectors |
| url | https://doi.org/10.1038/s41598-022-14940-1 |
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