Exposure assessment of Bisphenol A intake from polymeric baby bottles in formula-fed infants aged less than one year
BisphenolA (BPA) or 2,2-bis(4-hydroxyphenyl)propanepresent in polycarbonate baby bottles may have harmful effects for formula-fed infants. This study evaluated the risks associated with exposure to BPA among Iranian formula-fed infants in an urban society in Isfahan. New and used baby bottles (n = 7...
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| Format: | Article |
| Language: | English |
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Elsevier
2015-01-01
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| Series: | Toxicology Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214750015300561 |
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| author | Zohreh Abdi Moghadam Maryam Mirlohi Hamidreza Pourzamani Akbar Malekpour Zohreh Amininoor Mohammad Reza Merasi |
| author_facet | Zohreh Abdi Moghadam Maryam Mirlohi Hamidreza Pourzamani Akbar Malekpour Zohreh Amininoor Mohammad Reza Merasi |
| author_sort | Zohreh Abdi Moghadam |
| collection | DOAJ |
| description | BisphenolA (BPA) or 2,2-bis(4-hydroxyphenyl)propanepresent in polycarbonate baby bottles may have harmful effects for formula-fed infants. This study evaluated the risks associated with exposure to BPA among Iranian formula-fed infants in an urban society in Isfahan. New and used baby bottles (n = 7 and 8, respectively) as well as BPA-free marked bottles (n = 2) were collected from a retail outlet, and leaching of BPA was examined by conducting a migration test. Concentrations of BPA released from the new and used baby bottles were in the range of 0.49–8.58 and 0.63–2.47 μg/l, respectively. Next, probabilistic exposure estimation was performed. In all, 200 mothers registered with 11 health centres in Isfahan were interviewed. Data on feeding pattern, washing and sterilization practices, bottles types and manufacturers as well as the sex and weight of the infants were collected using a questionnaire. The results showed that majority of the surveyed infants were exposed to 0.1–0.3 μg/kg body weight (bw)/d of BPA, which corresponded to approximately 2–7.5% of the defined t-TDI (4 μg/kgbw/d). These results suggested that the risk of the adverse effects caused by exposure to BPA was very low in formula-fed Iranian infants even in the worst-case scenario. |
| first_indexed | 2024-12-10T18:21:00Z |
| format | Article |
| id | doaj.art-f14e12abe9f841f1ba94c4d844072038 |
| institution | Directory Open Access Journal |
| issn | 2214-7500 |
| language | English |
| last_indexed | 2024-12-10T18:21:00Z |
| publishDate | 2015-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Toxicology Reports |
| spelling | doaj.art-f14e12abe9f841f1ba94c4d8440720382022-12-22T01:38:13ZengElsevierToxicology Reports2214-75002015-01-012C1273128010.1016/j.toxrep.2015.09.002Exposure assessment of Bisphenol A intake from polymeric baby bottles in formula-fed infants aged less than one yearZohreh Abdi Moghadam0Maryam Mirlohi1Hamidreza Pourzamani2Akbar Malekpour3Zohreh Amininoor4Mohammad Reza Merasi5Food Security Research Center, Department of Food Sciences and Technology, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, IranFood Security Research Center, Department of Food Sciences and Technology, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, IranDepartment of Chemistry, University of Isfahan, Isfahan, IranEnvironment Research Center, Department of Environmental Health Engineering, Isfahan University of Medical Sciences (IUMS), Isfahan, IranSchool of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, IranDepartments of Epidemiology and Biostatistics, School of Health, Isfahan University of Medical Sciences, Isfahan, IranBisphenolA (BPA) or 2,2-bis(4-hydroxyphenyl)propanepresent in polycarbonate baby bottles may have harmful effects for formula-fed infants. This study evaluated the risks associated with exposure to BPA among Iranian formula-fed infants in an urban society in Isfahan. New and used baby bottles (n = 7 and 8, respectively) as well as BPA-free marked bottles (n = 2) were collected from a retail outlet, and leaching of BPA was examined by conducting a migration test. Concentrations of BPA released from the new and used baby bottles were in the range of 0.49–8.58 and 0.63–2.47 μg/l, respectively. Next, probabilistic exposure estimation was performed. In all, 200 mothers registered with 11 health centres in Isfahan were interviewed. Data on feeding pattern, washing and sterilization practices, bottles types and manufacturers as well as the sex and weight of the infants were collected using a questionnaire. The results showed that majority of the surveyed infants were exposed to 0.1–0.3 μg/kg body weight (bw)/d of BPA, which corresponded to approximately 2–7.5% of the defined t-TDI (4 μg/kgbw/d). These results suggested that the risk of the adverse effects caused by exposure to BPA was very low in formula-fed Iranian infants even in the worst-case scenario.http://www.sciencedirect.com/science/article/pii/S2214750015300561Bisphenol ARisk assessmentBaby bottleIran |
| spellingShingle | Zohreh Abdi Moghadam Maryam Mirlohi Hamidreza Pourzamani Akbar Malekpour Zohreh Amininoor Mohammad Reza Merasi Exposure assessment of Bisphenol A intake from polymeric baby bottles in formula-fed infants aged less than one year Toxicology Reports Bisphenol A Risk assessment Baby bottle Iran |
| title | Exposure assessment of Bisphenol A intake from polymeric baby bottles in formula-fed infants aged less than one year |
| title_full | Exposure assessment of Bisphenol A intake from polymeric baby bottles in formula-fed infants aged less than one year |
| title_fullStr | Exposure assessment of Bisphenol A intake from polymeric baby bottles in formula-fed infants aged less than one year |
| title_full_unstemmed | Exposure assessment of Bisphenol A intake from polymeric baby bottles in formula-fed infants aged less than one year |
| title_short | Exposure assessment of Bisphenol A intake from polymeric baby bottles in formula-fed infants aged less than one year |
| title_sort | exposure assessment of bisphenol a intake from polymeric baby bottles in formula fed infants aged less than one year |
| topic | Bisphenol A Risk assessment Baby bottle Iran |
| url | http://www.sciencedirect.com/science/article/pii/S2214750015300561 |
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