TET2 is required to suppress mTORC1 signaling through urea cycle with therapeutic potential

TET2 is required to suppress mTORC1 signaling through urea cycle with therapeutic potential

Abstract Tumor development, involving both cell growth (mass accumulation) and cell proliferation, is a complex process governed by the interplay of multiple signaling pathways. TET2 mainly functions as a DNA dioxygenase, which modulates gene expression and biological functions via oxidation of 5mC...

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ग्रंथसूची विवरण
मुख्य लेखकों: Jing He, Mingen Lin, Xinchao Zhang, Ruonan Zhang, Tongguan Tian, Yuefan Zhou, Wenjing Dong, Yajing Yang, Xue Sun, Yue Dai, Yue Xu, Zhenru Zhang, Ming Xu, Qun-Ying Lei, Yanping Xu, Lei Lv
स्वरूप: लेख
भाषा:English
प्रकाशित: Nature Publishing Group 2023-08-01
श्रृंखला:Cell Discovery
ऑनलाइन पहुंच:https://doi.org/10.1038/s41421-023-00567-7

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https://doi.org/10.1038/s41421-023-00567-7

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