Antibacterial Activity and Aphrodisiac Potential of the Ethanolic Extracts of Fadogia agretis (Sch winffax Hiern) Stem in Male Albino Rats

The research is aimed to evaluate the antibacterial activity and aphrodisiac potential of the ethanolic extracts of Fadogia agrestis (rubiaceae) stem in male albino rats. The antibacterial activity of the extracts were tested on four hospital isolates of staphylococcus aureus, Escherichia coli, Pseu...

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Main Author: Salihu Abdullahi Kiyawa
Format: Article
Language:English
Published: Laboratory of Organic Materials 2016-02-01
Series:Algerian Journal of Natural Products
Subjects:
Online Access:https://drive.google.com/file/d/0B5a53giHS_KpNTFfU1dJem8tazQ/view?pref=2&pli=1
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author Salihu Abdullahi Kiyawa
author_facet Salihu Abdullahi Kiyawa
author_sort Salihu Abdullahi Kiyawa
collection DOAJ
description The research is aimed to evaluate the antibacterial activity and aphrodisiac potential of the ethanolic extracts of Fadogia agrestis (rubiaceae) stem in male albino rats. The antibacterial activity of the extracts were tested on four hospital isolates of staphylococcus aureus, Escherichia coli, Pseudomonas specie and Proteus spp at a concentration of 500µg using disc diffusion method. For aphrodisiac test, healthy, white male albino rats (Rattis novergicus) weighing 270 300g aged 5.0 5.5 months and female albino rats weighing 150 180g aged 3.5 5.4 months were used for the study. The male albino rats were orally dosed with 50mg/kg, 100mg/kg and 200mg/kg body weight respectively of the extract at 24hours intervals. Their sexual behaviour was evaluated for 15 minutes each. The plants extract was found to inhibit staphylococcus aureus and Pseudomonas specie. Aphrodisiac effect of the extract resulted in significant increase in mount behaviour. The antibacterial effects suggest their possible use for the treatment of infection that showed in vitro susceptibility. Also, the increase in the mounting behavior may be responsible for the aphrodisiac effect.
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spelling doaj.art-f150902feb044189804559c22f77138e2022-12-21T17:44:00ZengLaboratory of Organic MaterialsAlgerian Journal of Natural Products2353-03912016-02-0141217225Antibacterial Activity and Aphrodisiac Potential of the Ethanolic Extracts of Fadogia agretis (Sch winffax Hiern) Stem in Male Albino RatsSalihu Abdullahi Kiyawa0Chemistry Department, Northwest University, PMB 3220, Kano – Nigeria.The research is aimed to evaluate the antibacterial activity and aphrodisiac potential of the ethanolic extracts of Fadogia agrestis (rubiaceae) stem in male albino rats. The antibacterial activity of the extracts were tested on four hospital isolates of staphylococcus aureus, Escherichia coli, Pseudomonas specie and Proteus spp at a concentration of 500µg using disc diffusion method. For aphrodisiac test, healthy, white male albino rats (Rattis novergicus) weighing 270 300g aged 5.0 5.5 months and female albino rats weighing 150 180g aged 3.5 5.4 months were used for the study. The male albino rats were orally dosed with 50mg/kg, 100mg/kg and 200mg/kg body weight respectively of the extract at 24hours intervals. Their sexual behaviour was evaluated for 15 minutes each. The plants extract was found to inhibit staphylococcus aureus and Pseudomonas specie. Aphrodisiac effect of the extract resulted in significant increase in mount behaviour. The antibacterial effects suggest their possible use for the treatment of infection that showed in vitro susceptibility. Also, the increase in the mounting behavior may be responsible for the aphrodisiac effect.https://drive.google.com/file/d/0B5a53giHS_KpNTFfU1dJem8tazQ/view?pref=2&pli=1Aphrodisiac potentialethanolic extractsfadogia agrestisalbino rats
spellingShingle Salihu Abdullahi Kiyawa
Antibacterial Activity and Aphrodisiac Potential of the Ethanolic Extracts of Fadogia agretis (Sch winffax Hiern) Stem in Male Albino Rats
Algerian Journal of Natural Products
Aphrodisiac potential
ethanolic extracts
fadogia agrestis
albino rats
title Antibacterial Activity and Aphrodisiac Potential of the Ethanolic Extracts of Fadogia agretis (Sch winffax Hiern) Stem in Male Albino Rats
title_full Antibacterial Activity and Aphrodisiac Potential of the Ethanolic Extracts of Fadogia agretis (Sch winffax Hiern) Stem in Male Albino Rats
title_fullStr Antibacterial Activity and Aphrodisiac Potential of the Ethanolic Extracts of Fadogia agretis (Sch winffax Hiern) Stem in Male Albino Rats
title_full_unstemmed Antibacterial Activity and Aphrodisiac Potential of the Ethanolic Extracts of Fadogia agretis (Sch winffax Hiern) Stem in Male Albino Rats
title_short Antibacterial Activity and Aphrodisiac Potential of the Ethanolic Extracts of Fadogia agretis (Sch winffax Hiern) Stem in Male Albino Rats
title_sort antibacterial activity and aphrodisiac potential of the ethanolic extracts of fadogia agretis sch winffax hiern stem in male albino rats
topic Aphrodisiac potential
ethanolic extracts
fadogia agrestis
albino rats
url https://drive.google.com/file/d/0B5a53giHS_KpNTFfU1dJem8tazQ/view?pref=2&pli=1
work_keys_str_mv AT salihuabdullahikiyawa antibacterialactivityandaphrodisiacpotentialoftheethanolicextractsoffadogiaagretisschwinffaxhiernsteminmalealbinorats