The Great Debate at ‘Immunotherapy Bridge’, Naples, December 5, 2019

As part of the 2019 Immunotherapy Bridge congress (December 4–5, Naples, Italy), the Great Debate session featured counterpoint views from leading experts on six topical issues in immunotherapy today. These were the use of chimeric antigen receptor T cell therapy in solid tumors, whether the Immunos...

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Main Authors: Jerome Galon, Chrystal M Paulos, Sergio A Quezada, Hussein A Tawbi
Format: Article
Language:English
Published: BMJ Publishing Group 2020-07-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/2/e000921.full
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author Jerome Galon
Chrystal M Paulos
Sergio A Quezada
Hussein A Tawbi
author_facet Jerome Galon
Chrystal M Paulos
Sergio A Quezada
Hussein A Tawbi
author_sort Jerome Galon
collection DOAJ
description As part of the 2019 Immunotherapy Bridge congress (December 4–5, Naples, Italy), the Great Debate session featured counterpoint views from leading experts on six topical issues in immunotherapy today. These were the use of chimeric antigen receptor T cell therapy in solid tumors, whether the Immunoscore should be more widely used in clinical practice, whether antibody-dependent cellular cytotoxicity is important in the mode of action of anticytotoxic T-lymphocyte-associated protein 4 antibodies, whether the brain is immunologically unique or just another organ, the role of microbiome versus nutrition in affecting responses to immunotherapy, and whether chemotherapy is immunostimulatory or immunosuppressive. Discussion of these important topics are summarized in this report.
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spelling doaj.art-f159b1b615c54c22ad0cfb29a9b81a272022-12-21T18:32:54ZengBMJ Publishing GroupJournal for ImmunoTherapy of Cancer2051-14262020-07-018210.1136/jitc-2020-000921The Great Debate at ‘Immunotherapy Bridge’, Naples, December 5, 2019Jerome Galon0Chrystal M Paulos1Sergio A Quezada2Hussein A Tawbi3Laboratory of Integrative Cancer Immunology, Equipe Labellisée Ligue Contre le Cancer, Centre de Recherche des Cordeliers, INSERM, Paris, Île-de-France, FranceDepartment of Microbiology and Immunology Hollings Cancer Center, MUSC, Charleston, South Carolina, USACancer Immunology Unit, Research Department of Haematology, University College London Cancer Institute, London, UKDepartment of Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USAAs part of the 2019 Immunotherapy Bridge congress (December 4–5, Naples, Italy), the Great Debate session featured counterpoint views from leading experts on six topical issues in immunotherapy today. These were the use of chimeric antigen receptor T cell therapy in solid tumors, whether the Immunoscore should be more widely used in clinical practice, whether antibody-dependent cellular cytotoxicity is important in the mode of action of anticytotoxic T-lymphocyte-associated protein 4 antibodies, whether the brain is immunologically unique or just another organ, the role of microbiome versus nutrition in affecting responses to immunotherapy, and whether chemotherapy is immunostimulatory or immunosuppressive. Discussion of these important topics are summarized in this report.https://jitc.bmj.com/content/8/2/e000921.full
spellingShingle Jerome Galon
Chrystal M Paulos
Sergio A Quezada
Hussein A Tawbi
The Great Debate at ‘Immunotherapy Bridge’, Naples, December 5, 2019
Journal for ImmunoTherapy of Cancer
title The Great Debate at ‘Immunotherapy Bridge’, Naples, December 5, 2019
title_full The Great Debate at ‘Immunotherapy Bridge’, Naples, December 5, 2019
title_fullStr The Great Debate at ‘Immunotherapy Bridge’, Naples, December 5, 2019
title_full_unstemmed The Great Debate at ‘Immunotherapy Bridge’, Naples, December 5, 2019
title_short The Great Debate at ‘Immunotherapy Bridge’, Naples, December 5, 2019
title_sort great debate at immunotherapy bridge naples december 5 2019
url https://jitc.bmj.com/content/8/2/e000921.full
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