Cell-Specific “Competition for Calories” Drives Asymmetric Nutrient-Energy Partitioning, Obesity, and Metabolic Diseases in Human and Non-human Animals

Cell-Specific “Competition for Calories” Drives Asymmetric Nutrient-Energy Partitioning, Obesity, and Metabolic Diseases in Human and Non-human Animals

The mammalian body is a complex physiologic “ecosystem” in which cells compete for calories (i.e., nutrient-energy). Axiomatically, cell-types with competitive advantages acquire a greater number of consumed calories, and when possible, increase in size and/or number. Thus, it is logical and parsimo...

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Bibliographic Details
Main Authors: Edward Archer, Gregory Pavela, Samantha McDonald, Carl J. Lavie, James O. Hill
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Physiology
Subjects:
obesity
nutrition
physiology
non-genetic
evolution
competition
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01053/full

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