Tailored Treatment Options for Cerebral Cavernous Malformations

The diagnosis and treatment of cerebral cavernous malformations (CCMs), or cavernomas, continues to evolve as more data and treatment modalities become available. Intervention is necessary when a lesion causes symptomatic neurologic deficits, seizures, or has high risk of continued hemorrhage. Futur...

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Main Authors: Jessa E. Hoffman, Blake Wittenberg, Brent Morel, Zach Folzenlogen, David Case, Christopher Roark, Samy Youssef, Joshua Seinfeld
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Journal of Personalized Medicine
Subjects:
Online Access:https://www.mdpi.com/2075-4426/12/5/831
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author Jessa E. Hoffman
Blake Wittenberg
Brent Morel
Zach Folzenlogen
David Case
Christopher Roark
Samy Youssef
Joshua Seinfeld
author_facet Jessa E. Hoffman
Blake Wittenberg
Brent Morel
Zach Folzenlogen
David Case
Christopher Roark
Samy Youssef
Joshua Seinfeld
author_sort Jessa E. Hoffman
collection DOAJ
description The diagnosis and treatment of cerebral cavernous malformations (CCMs), or cavernomas, continues to evolve as more data and treatment modalities become available. Intervention is necessary when a lesion causes symptomatic neurologic deficits, seizures, or has high risk of continued hemorrhage. Future medical treatment directions may specifically target the pathogenesis of these lesions. This review highlights the importance of individualized treatment plans based on specific CCM characteristics.
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spelling doaj.art-f15ce917551b4c779dc1e3a8fe4e3a832023-11-23T11:45:30ZengMDPI AGJournal of Personalized Medicine2075-44262022-05-0112583110.3390/jpm12050831Tailored Treatment Options for Cerebral Cavernous MalformationsJessa E. Hoffman0Blake Wittenberg1Brent Morel2Zach Folzenlogen3David Case4Christopher Roark5Samy Youssef6Joshua Seinfeld7Department of Neurosurgery, University of Colorado, Aurora, CO 80045, USADepartment of Neurosurgery, University of Colorado, Aurora, CO 80045, USADepartment of Neurosurgery, University of Colorado, Aurora, CO 80045, USADepartment of Neurosurgery, University of Colorado, Aurora, CO 80045, USADepartment of Neurosurgery, University of Colorado, Aurora, CO 80045, USADepartment of Neurosurgery, University of Colorado, Aurora, CO 80045, USADepartment of Neurosurgery, University of Colorado, Aurora, CO 80045, USADepartment of Neurosurgery, University of Colorado, Aurora, CO 80045, USAThe diagnosis and treatment of cerebral cavernous malformations (CCMs), or cavernomas, continues to evolve as more data and treatment modalities become available. Intervention is necessary when a lesion causes symptomatic neurologic deficits, seizures, or has high risk of continued hemorrhage. Future medical treatment directions may specifically target the pathogenesis of these lesions. This review highlights the importance of individualized treatment plans based on specific CCM characteristics.https://www.mdpi.com/2075-4426/12/5/831cerebral cavernous malformationsCCMscavernomas
spellingShingle Jessa E. Hoffman
Blake Wittenberg
Brent Morel
Zach Folzenlogen
David Case
Christopher Roark
Samy Youssef
Joshua Seinfeld
Tailored Treatment Options for Cerebral Cavernous Malformations
Journal of Personalized Medicine
cerebral cavernous malformations
CCMs
cavernomas
title Tailored Treatment Options for Cerebral Cavernous Malformations
title_full Tailored Treatment Options for Cerebral Cavernous Malformations
title_fullStr Tailored Treatment Options for Cerebral Cavernous Malformations
title_full_unstemmed Tailored Treatment Options for Cerebral Cavernous Malformations
title_short Tailored Treatment Options for Cerebral Cavernous Malformations
title_sort tailored treatment options for cerebral cavernous malformations
topic cerebral cavernous malformations
CCMs
cavernomas
url https://www.mdpi.com/2075-4426/12/5/831
work_keys_str_mv AT jessaehoffman tailoredtreatmentoptionsforcerebralcavernousmalformations
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AT zachfolzenlogen tailoredtreatmentoptionsforcerebralcavernousmalformations
AT davidcase tailoredtreatmentoptionsforcerebralcavernousmalformations
AT christopherroark tailoredtreatmentoptionsforcerebralcavernousmalformations
AT samyyoussef tailoredtreatmentoptionsforcerebralcavernousmalformations
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