COMPARISON OF OBESITY RELATED CARDIOMETABOLIC RISKS IN DIABETES TYPE 1 AND 2
Diabetes mellitus (DM) regardless the type is a disease with very high cardiovascular complications rate (CVC). With the increase of obesity prevalence in the whole world, there is increase of DM type 1 number (DM1) with overweight as well. Taken DM1, obesity usually is not considered as a risk fact...
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2017-05-01
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| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/1545 |
| _version_ | 1797856919051829248 |
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| author | N. V. Leonova G. A. Chumakova A. V. Tsirikova |
| author_facet | N. V. Leonova G. A. Chumakova A. V. Tsirikova |
| author_sort | N. V. Leonova |
| collection | DOAJ |
| description | Diabetes mellitus (DM) regardless the type is a disease with very high cardiovascular complications rate (CVC). With the increase of obesity prevalence in the whole world, there is increase of DM type 1 number (DM1) with overweight as well. Taken DM1, obesity usually is not considered as a risk factor for CVC.Aim. To study the prevalence of overweight and obesity, and influence on the risk of myocardial infarction development (MI), or stroke in DM1 and type 2 (DM2) patients with various metabolic phenotypes; and to evaluate gender specifics.Material and methods. Patients with DM1 were included, totally 3190 persons, and DM2, totally 71602 persons. All DM patients were selected to 3 subgroups: group 1 — normal bodyweight, group 2 — overweight, and group 3 — obese. In each group the prevalence of MI and stroke was evaluated, and risk estimated.Results. Among DM1 patients with overweight were 29,3% (men 29,0%, women 29,7%). Obesity was registered in 9,7% DM1. In difference with overweight, obesity was registered 2 times more commonly and significantly in men, than in women (6,8% vs. 13,4%; p<0,001). In DM1 patients there were no gender differences; in DM2 patients the prevalence of these complications was statistically more significant and higher in men than in women. Overweight and obesity do not increase risk of MI and stroke in DM2. In DM1 overweight increases 2,4 times the risk of stroke, but not MI; obesity does increase 5,2 times the risk of MI, but only in men. The risk of stroke in DM1 and obesity increases 2,8 times, but only in women. Presence of obesity metabolic phenotype in DM1 increases the risk of MI and stroke, nullifying gender differences.Conclusion. Overweight and obesity do influence differently the CVC risk in DM1 and 2. Prevention and treatment of overweight and obesity, together with carbohydrate metabolism disorder, should be the fundamentals of cardiovascular risk decrease in DM1. |
| first_indexed | 2024-04-09T20:48:21Z |
| format | Article |
| id | doaj.art-f15cefe0fb9d4bde8a9e440030c67a03 |
| institution | Directory Open Access Journal |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| last_indexed | 2024-04-09T20:48:21Z |
| publishDate | 2017-05-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj.art-f15cefe0fb9d4bde8a9e440030c67a032023-03-29T21:23:28Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202017-05-0104475310.15829/1560-4071-2017-4-47-531328COMPARISON OF OBESITY RELATED CARDIOMETABOLIC RISKS IN DIABETES TYPE 1 AND 2N. V. Leonova0G. A. Chumakova1A. V. Tsirikova2LLC MMC AnturiumФГБОУ ВО Алтайский государственный медицинский университет МЗ России; ФГБНУ НИИ комплексных проблем сердечно-сосудистых заболеванийAltai State Medical University of the Ministry of HealthDiabetes mellitus (DM) regardless the type is a disease with very high cardiovascular complications rate (CVC). With the increase of obesity prevalence in the whole world, there is increase of DM type 1 number (DM1) with overweight as well. Taken DM1, obesity usually is not considered as a risk factor for CVC.Aim. To study the prevalence of overweight and obesity, and influence on the risk of myocardial infarction development (MI), or stroke in DM1 and type 2 (DM2) patients with various metabolic phenotypes; and to evaluate gender specifics.Material and methods. Patients with DM1 were included, totally 3190 persons, and DM2, totally 71602 persons. All DM patients were selected to 3 subgroups: group 1 — normal bodyweight, group 2 — overweight, and group 3 — obese. In each group the prevalence of MI and stroke was evaluated, and risk estimated.Results. Among DM1 patients with overweight were 29,3% (men 29,0%, women 29,7%). Obesity was registered in 9,7% DM1. In difference with overweight, obesity was registered 2 times more commonly and significantly in men, than in women (6,8% vs. 13,4%; p<0,001). In DM1 patients there were no gender differences; in DM2 patients the prevalence of these complications was statistically more significant and higher in men than in women. Overweight and obesity do not increase risk of MI and stroke in DM2. In DM1 overweight increases 2,4 times the risk of stroke, but not MI; obesity does increase 5,2 times the risk of MI, but only in men. The risk of stroke in DM1 and obesity increases 2,8 times, but only in women. Presence of obesity metabolic phenotype in DM1 increases the risk of MI and stroke, nullifying gender differences.Conclusion. Overweight and obesity do influence differently the CVC risk in DM1 and 2. Prevention and treatment of overweight and obesity, together with carbohydrate metabolism disorder, should be the fundamentals of cardiovascular risk decrease in DM1.https://russjcardiol.elpub.ru/jour/article/view/1545overweightobesitymyocardial infarctionstrokediabetes mellitus types 1 and 2 |
| spellingShingle | N. V. Leonova G. A. Chumakova A. V. Tsirikova COMPARISON OF OBESITY RELATED CARDIOMETABOLIC RISKS IN DIABETES TYPE 1 AND 2 Российский кардиологический журнал overweight obesity myocardial infarction stroke diabetes mellitus types 1 and 2 |
| title | COMPARISON OF OBESITY RELATED CARDIOMETABOLIC RISKS IN DIABETES TYPE 1 AND 2 |
| title_full | COMPARISON OF OBESITY RELATED CARDIOMETABOLIC RISKS IN DIABETES TYPE 1 AND 2 |
| title_fullStr | COMPARISON OF OBESITY RELATED CARDIOMETABOLIC RISKS IN DIABETES TYPE 1 AND 2 |
| title_full_unstemmed | COMPARISON OF OBESITY RELATED CARDIOMETABOLIC RISKS IN DIABETES TYPE 1 AND 2 |
| title_short | COMPARISON OF OBESITY RELATED CARDIOMETABOLIC RISKS IN DIABETES TYPE 1 AND 2 |
| title_sort | comparison of obesity related cardiometabolic risks in diabetes type 1 and 2 |
| topic | overweight obesity myocardial infarction stroke diabetes mellitus types 1 and 2 |
| url | https://russjcardiol.elpub.ru/jour/article/view/1545 |
| work_keys_str_mv | AT nvleonova comparisonofobesityrelatedcardiometabolicrisksindiabetestype1and2 AT gachumakova comparisonofobesityrelatedcardiometabolicrisksindiabetestype1and2 AT avtsirikova comparisonofobesityrelatedcardiometabolicrisksindiabetestype1and2 |