Summary: | Purpose: There is still no comprehensive analysis with Bulgarian patients investigating the association
between perioperative clinical parameters and final outcome in the early phase of complicated intraabdominal infection.
Methods: This single-center prospective study was conducted in the Clinic of Surgical Diseases at the
University Hospital Stara-Zagora for the period November 2018 - August 2021. Before surgery and on
the 3rd postoperative day (POD) we measured axillary temperature (t), systolic blood pressure (SBP),
mean arterial pressure (MAP), respiratory rate (RR), heart rate (HR), mental status and systemic
inflammatory response syndrome (SIRS) in 62 patients with complicated intra-abdominal infections
(cIAIs).
Results: Of the 62 patients, nine died (14.5%). Preoperatively, only MAP successfully discriminated
survivors from non-survivors (p = 0.027), which was confirmed by the ROC Curve analysis (AUROC =
0.731). Postoperatively, almost all of the clinical parameters except axillary temperature (AUROC =
0.573) showed prognostic ability – SBP (AUROC = 0.779) and MAP (AUROC = 0.864) for prediction
of favorable outcome, HR (AUROC = 0.916) and RR (AUROC = 0.935) for prediction of lethal outcome.
Conclusion: All investigated clinical parameters, except for axillary temperature, demonstrated the
ability to predict the final outcome on the 3
rd POD in patients with cIAIs.
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